Detailed information of TA system TA227562

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 562701..563334
• Replicon: chromosome
• Accession: NZ_CP089051
• Organism: Acinetobacter ursingii strain RIVM_C010559

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: LSO60_RS02795
• Protein ID: WP_263512843.1
• Coordinates: 562951..563334 (+)
• Length: 128 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A2N6VED5
• Locus tag: LSO60_RS02790
• Protein ID: WP_004985373.1
• Coordinates: 562701..562958 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LSO60_RS02770 (LSO60_02770)	558200..559207	+	1008	WP_004924164.1	DNA-directed RNA polymerase subunit alpha	-
LSO60_RS02775 (LSO60_02775)	559226..559603	+	378	WP_004924167.1	50S ribosomal protein L17	-
LSO60_RS02780 (LSO60_02780)	559771..561267	+	1497	WP_263512841.1	NAD(P)/FAD-dependent oxidoreductase	-
LSO60_RS02785 (LSO60_02785)	561340..562512	-	1173	WP_263512842.1	acyl-CoA dehydrogenase family protein	-
LSO60_RS02790 (LSO60_02790)	562701..562958	+	258	WP_004985373.1	succinate dehydrogenase assembly factor 2	Antitoxin
LSO60_RS02795 (LSO60_02795)	562951..563334	+	384	WP_263512843.1	hypothetical protein	Toxin
LSO60_RS02800 (LSO60_02800)	563877..565001	+	1125	WP_151833082.1	hypothetical protein	-
LSO60_RS02805 (LSO60_02805)	565114..565707	+	594	WP_263512844.1	rhombosortase	-
LSO60_RS02810 (LSO60_02810)	565863..568061	+	2199	WP_010588897.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 128 a.a.
• Molecular weight: 15413.49 Da
• Isoelectric Point: 10.6981

>T227562 WP_263512843.1 NZ_CP089051:562951-563334 [Acinetobacter ursingii]
MVNHQFQLKRSLLALLFQLGMLLLIGIIWFQLFPFYMSLSAIFLAIIAYLAFLRRSKMCSLAYLDQDLWSIRWRNHSKIE
HVQLYRVIDHHIYIVLYFKQNRNSQIIWRDQVSLNQWKQLKVMAKLV

Nucleotide

• Length: 384 bp

>T227562 NZ_CP122951:20225-20989 [Helicobacter pylori]
ATGGAAATTAAAGAAGAGGATAAAGATAAAAAGCTAGAAAAAATTATTGTATTGCTGTGTGAAAAGGGGGATTTGTCTAG
CCAAAAAGATCAAATCATCAAAGATCTCAAAGAAATCTATAAAGGAGAATACAAGCATAAATACTCAAAAATCACAACTA
TTATTTTAAATTCCACAAGGGATAAAGAGCAAGCCTTTATGATGCTCACACAAAATATAAAGACGCTCAAAGAGATTCAA
GATAATAAAGAAGTTGAAAGCATTAAACCAAAACTAGAAAAGCTTTATGATCACATGAATTTAGAGTGTATCAGACTGCA
AGATTTTGATGAGAAAATGAGTAGAGTTAAAGATGTTTCTATAAAGTTAGAAGATGAACTAAATAAAAACTATAAAAAAT
TAAGCGAAGAATTGAATAAGCAACAAACACAATACATAACCATTTTAGGTATTTTTGCCTCTATTGTTTTAACATTTGTT
GGGGGATTGGCGTTTTCCACTTCTGTTTTATCAAATATTGACAAAGCGAACGCCTATCGTTTGGTTTTTGTTATGGCTTT
TATAGCTTTATTTTTTGGGAATATTTTGTATCTGCTTTTTTCTTTTTTATCAAAAATATCCTTATCAGAAGAGAAAAAAG
ATAAACAAGAAAATTTTTTCAAAAAACCTATTTTTTGGTTTAATCTAATAGTTACAATTCTATTTGTGATTGGTTTTTGT
GGAGAATTGCATATAATACAGAGATTAGCTTCTAAATATTTTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10137.60 Da
• Isoelectric Point: 4.7414

>AT227562 WP_004985373.1 NZ_CP089051:562701-562958 [Acinetobacter ursingii]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVRNHYLSAEPAEKALFAELVDQEDPDLLDWFMEVSEPPKPELKTFILKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT227562 NZ_CP122951:19798-20235 [Helicobacter pylori]
ATGGTCAATACTTTGGAACTAGCAAAATATATTCTTAAGCATTCCAACAAAGAATTGAGTAACTTAGAATTGCAAAAAAC
TTTGTATTTCACAGAGCTTGACTATATCAAAAAGTTTGACAAACACCTAGTTTCTGATGATTTTGAAGCTTGGAAATACG
GGCCTGTTGCAAGGGAAGTGTATTATGAATATCGCAATTATGGTGCCAATTCTATTGACAAACCTAAAGAAGAAACGCTC
TCACAAGATCTTAGAGAAGATGAACTTGAAACCATCAATCGCTCCATAAAAAAATGCAACGAAAAATCCTATTGGGATTT
AGTGAAAGAGAGTCATAAAGAAGATGGCGCTTGGCATAAAAGCTTCAAAGAAGATAGAAAAGAAATCATTAGCAAAGATT
TGATCAAACAAGAAGCAAAACAAGCAAATGGAAATTAA

Structures

Antitoxin

• AlphaFold DB: A0A2N6VED5