Detailed information of TA system TA227555

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 564498..565131
• Replicon: chromosome
• Accession: NZ_CP089044
• Organism: Acinetobacter ursingii strain RIVM_C010761

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: LSO58_RS02635
• Protein ID: WP_010588898.1
• Coordinates: 564748..565131 (+)
• Length: 128 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A2N6VED5
• Locus tag: LSO58_RS02630
• Protein ID: WP_004985373.1
• Coordinates: 564498..564755 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LSO58_RS02610 (LSO58_02605)	559996..561003	+	1008	WP_004924164.1	DNA-directed RNA polymerase subunit alpha	-
LSO58_RS02615 (LSO58_02610)	561022..561399	+	378	WP_004924167.1	50S ribosomal protein L17	-
LSO58_RS02620 (LSO58_02615)	561567..563063	+	1497	WP_004985369.1	NAD(P)/FAD-dependent oxidoreductase	-
LSO58_RS02625 (LSO58_02620)	563137..564309	-	1173	WP_004985371.1	acyl-CoA dehydrogenase family protein	-
LSO58_RS02630 (LSO58_02625)	564498..564755	+	258	WP_004985373.1	succinate dehydrogenase assembly factor 2	Antitoxin
LSO58_RS02635 (LSO58_02630)	564748..565131	+	384	WP_010588898.1	hypothetical protein	Toxin
LSO58_RS02640 (LSO58_02635)	565674..566798	+	1125	WP_004985378.1	hypothetical protein	-
LSO58_RS02645 (LSO58_02640)	566911..567504	+	594	WP_004985380.1	rhombosortase	-
LSO58_RS02650 (LSO58_02645)	567661..569859	+	2199	WP_010588897.1	TRAP transporter large permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 128 a.a.
• Molecular weight: 15506.62 Da
• Isoelectric Point: 10.8548

>T227555 WP_010588898.1 NZ_CP089044:564748-565131 [Acinetobacter ursingii]
MVNHQFQLKRSLLALLFQLGMLLLIGIIWFQLFPFYIFLIAIFLAIIAYLAFLRRSKMRSLAYLDQDLWSIQWRNHSKIE
HVQLYRVIDHHIYIVLYFKQNRNSQIIWRDQVSLNQWKQLKVMAKLV

Nucleotide

• Length: 384 bp

>T227555 NZ_CP122946:c1079136-1078870 [Helicobacter pylori]
ATGCTGAAAATTAAGCACCATATCCTTTACAAAAAAGATTTTAAAAAACTTGTTAAAAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAACCTTAAGAAAGAAAGAACCGCTACCCCCACAATTTCAAGATCATGCCTTAAAGGGAAAGTGGA
AACCTTTTAGGGAATGCCACATCAAAGCCGATATTTTGCTTGTGTATTTAGTGAAAGATGATGAACTAATTTTAGTAAGA
CTAGGCAGTCATAGCGAGCTGTTTTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10137.60 Da
• Isoelectric Point: 4.7414

>AT227555 WP_004985373.1 NZ_CP089044:564498-564755 [Acinetobacter ursingii]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVRNHYLSAEPAEKALFAELVDQEDPDLLDWFMEVSEPPKPELKTFILKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT227555 NZ_CP122946:c1078789-1078412 [Helicobacter pylori]
ATGCCTAACACCACCGCCAAAAAAGACTACACACAATACAGCGAAAAACAGCTTTTTAACTTAATCAACCAATTAGAGCA
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGACAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGGACTCTTGCAAAAAATCAGCCAAGCTTTTGATGATAAAAGAGATTGTTGTTTG
GGGCGCAAGATCCCAAACCTTGAAACGCAACAAGCCATGAGAGATGCGCTTAACAAAGAAACCGATTTGATTGTTGAGGA
TTTTTCTAGTTATAGCGATGAAAGAAAAAGGGCGTTAGGTGTTGAAACTCAACCTTAA

Structures

Antitoxin

• AlphaFold DB: A0A2N6VED5