Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2289366..2289637 Replicon chromosome
Accession NZ_CP089032
Organism Escherichia coli O157:H7 strain 6535WT

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2289496..2289599 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2289366..2289637 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LSI69_RS11485 2285921..2286583 - 663 WP_000944243.1 exodeoxyribonuclease X -
LSI69_RS11490 2286607..2287263 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
LSI69_RS11495 2287365..2287595 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LSI69_RS11500 2287734..2288108 + 375 WP_000168751.1 CopC domain-containing protein YobA -
LSI69_RS11505 2288112..2288984 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
LSI69_RS11510 2288997..2289338 + 342 WP_000976483.1 YebY family protein -
- 2289366..2289637 - 272 - - Antitoxin
- 2289496..2289599 + 104 - - Toxin
LSI69_RS11515 2289734..2290390 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
LSI69_RS11520 2290391..2290582 - 192 WP_001296140.1 YebW family protein -
LSI69_RS11525 2290687..2290923 - 237 WP_001295499.1 YebV family protein -
LSI69_RS11530 2291041..2292480 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T227468 NZ_CP089032:2289496-2289599 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT227468 NZ_CP089032:c2289637-2289366 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References