Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 5603166..5603962 Replicon chromosome
Accession NC_010506
Organism Shewanella woodyi ATCC 51908

Toxin (Protein)


Gene name - Uniprot ID B1KM03
Locus tag SWOO_RS23760 Protein ID WP_012327207.1
Coordinates 5603432..5603962 (+) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID B1KM02
Locus tag SWOO_RS23755 Protein ID WP_005423939.1
Coordinates 5603166..5603435 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SWOO_RS23730 5598464..5598832 + 369 WP_041417842.1 hypothetical protein -
SWOO_RS23735 5598829..5599869 + 1041 WP_012327203.1 AAA family ATPase -
SWOO_RS23740 5600021..5600758 + 738 WP_012327204.1 hypothetical protein -
SWOO_RS23745 5601088..5601963 + 876 WP_012327205.1 toll/interleukin-1 receptor domain-containing protein -
SWOO_RS23750 5602032..5603006 + 975 WP_012327206.1 hypothetical protein -
SWOO_RS23755 5603166..5603435 + 270 WP_005423939.1 DUF1778 domain-containing protein Antitoxin
SWOO_RS23760 5603432..5603962 + 531 WP_012327207.1 GNAT family N-acetyltransferase Toxin
SWOO_RS23770 5604579..5606180 + 1602 WP_012327208.1 PDZ domain-containing protein -
SWOO_RS23775 5606186..5606581 + 396 WP_012327209.1 hypothetical protein -
SWOO_RS23785 5607091..5607954 - 864 WP_012327211.1 pyridoxal kinase PdxY -
SWOO_RS23790 5608118..5608345 + 228 WP_012327212.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19871.11 Da        Isoelectric Point: 8.7689

>T22745 WP_012327207.1 NC_010506:5603432-5603962 [Shewanella woodyi ATCC 51908]
VSYAKTFKELDKSQHDRASFDCGEKELNDFIQTQAAKHMQAGISRTMVLPASVPLPNQKYPICSFYSIAPSSISRDTLPQ
AMAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIKALEYLWEINSHMRAYSIVVDCLTEQAESFYAKYGFEVLCEING
RVRMFIPMKTVGQLFT

Download         Length: 531 bp

>T22745 NC_010506:5603432-5603962 [Shewanella woodyi ATCC 51908]
GTGAGTTATGCCAAGACTTTTAAAGAATTGGATAAATCACAACACGATAGAGCATCATTTGACTGTGGCGAAAAAGAGCT
AAACGACTTTATCCAAACTCAAGCAGCTAAACATATGCAAGCAGGTATTAGCCGCACTATGGTTTTACCTGCTTCTGTGC
CACTACCAAATCAAAAATATCCAATTTGTTCGTTTTATAGCATCGCGCCAAGTTCAATTAGCCGTGATACGTTGCCACAA
GCGATGGCTAAAAAATTACCGCGCTATCCCATTCCTGTTTTCCTTTTAGCTCAACTGGCAGTTCATAAAGAATTTCATGG
CAGTGGATTAGGTAAAGTTAGCTTAATCAAAGCCCTAGAATATCTTTGGGAAATTAACTCTCATATGAGAGCTTATTCCA
TTGTTGTTGATTGTTTAACTGAGCAAGCAGAGTCATTTTACGCAAAATATGGTTTCGAAGTTCTTTGTGAAATCAACGGC
CGTGTAAGAATGTTCATTCCGATGAAAACAGTCGGTCAGTTATTTACTTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9807.19 Da        Isoelectric Point: 4.4290

>AT22745 WP_005423939.1 NC_010506:5603166-5603435 [Shewanella woodyi ATCC 51908]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDSTQVISEHESITVEANVFDQFMIACDEAKAPNKALLEAA
AFTKSGEFK

Download         Length: 270 bp

>AT22745 NC_010506:5603166-5603435 [Shewanella woodyi ATCC 51908]
ATGGCTACTGCAAGACTTGATATCCGTTTGGATGAAGAAATCAAAGCTAAGGCTGAGAAAGCTTCAGCTTTACTTGGTTT
AAAAAGTTTAACTGAATACGTTGTTCGTTTAATGGACGAAGATTCAACTCAGGTGATTTCTGAACATGAAAGCATCACTG
TTGAAGCAAATGTATTTGACCAATTCATGATTGCTTGTGACGAGGCTAAGGCTCCGAATAAAGCATTACTCGAAGCTGCG
GCATTTACTAAAAGTGGTGAATTTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB B1KM03

Antitoxin

Source ID Structure
AlphaFold DB A0A1B9PGK1

References