Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2085390..2085535 Replicon chromosome
Accession NZ_CP089024
Organism Klebsiella pneumoniae strain 49210

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2085426..2085528 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2085390..2085535 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRY78_RS10025 2080520..2082580 + 2061 WP_004151449.1 oligopeptidase B -
LRY78_RS10030 2082584..2083243 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRY78_RS10035 2083322..2083552 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRY78_RS10040 2083665..2084039 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LRY78_RS10045 2084043..2084912 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
LRY78_RS10050 2084929..2085267 + 339 WP_002911404.1 YebY family protein -
- 2085390..2085535 - 146 - - Antitoxin
- 2085426..2085528 + 103 - - Toxin
LRY78_RS10055 2085903..2086046 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LRY78_RS10060 2086151..2087119 - 969 WP_014907334.1 VirK/YbjX family protein -
LRY78_RS10065 2087276..2087929 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LRY78_RS10070 2087926..2088117 - 192 WP_002911395.1 YebW family protein -
LRY78_RS10075 2088215..2088454 - 240 WP_002911393.1 YebV family protein -
LRY78_RS10080 2088570..2090003 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227409 NZ_CP089024:2085426-2085528 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227409 NZ_CP089024:c2085535-2085390 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References