Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1816922..1817067 Replicon chromosome
Accession NZ_CP089012
Organism Klebsiella pneumoniae strain 56575

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1816958..1817060 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1816922..1817067 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ79_RS08750 1812052..1814112 + 2061 WP_004151449.1 oligopeptidase B -
LRZ79_RS08755 1814116..1814775 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRZ79_RS08760 1814854..1815084 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRZ79_RS08765 1815197..1815571 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LRZ79_RS08770 1815575..1816444 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LRZ79_RS08775 1816461..1816799 + 339 WP_002911404.1 YebY family protein -
- 1816922..1817067 - 146 - - Antitoxin
- 1816958..1817060 + 103 - - Toxin
LRZ79_RS08780 1817434..1817577 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LRZ79_RS08785 1817682..1818650 - 969 WP_004151446.1 VirK/YbjX family protein -
LRZ79_RS08790 1818807..1819460 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
LRZ79_RS08795 1819457..1819648 - 192 WP_002911395.1 YebW family protein -
LRZ79_RS08800 1819746..1819985 - 240 WP_002911393.1 YebV family protein -
LRZ79_RS08805 1820101..1821534 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227343 NZ_CP089012:1816958-1817060 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227343 NZ_CP089012:c1817067-1816922 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References