Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1960955..1961100 Replicon chromosome
Accession NZ_CP089001
Organism Klebsiella pneumoniae strain 56661

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1960991..1961093 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1960955..1961100 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ77_RS09560 1956085..1958145 + 2061 WP_004151449.1 oligopeptidase B -
LRZ77_RS09565 1958149..1958808 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRZ77_RS09570 1958887..1959117 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRZ77_RS09575 1959230..1959604 + 375 WP_039819395.1 CopC domain-containing protein YobA -
LRZ77_RS09580 1959608..1960477 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LRZ77_RS09585 1960494..1960832 + 339 WP_002911404.1 YebY family protein -
- 1960955..1961100 - 146 - - Antitoxin
- 1960991..1961093 + 103 - - Toxin
LRZ77_RS09590 1961469..1961612 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
LRZ77_RS09595 1961717..1962685 - 969 WP_014907334.1 VirK/YbjX family protein -
LRZ77_RS09600 1962842..1963495 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
LRZ77_RS09605 1963492..1963683 - 192 WP_002911395.1 YebW family protein -
LRZ77_RS09610 1963781..1964020 - 240 WP_231821752.1 YebV family protein -
LRZ77_RS09615 1964136..1965569 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227318 NZ_CP089001:1960991-1961093 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227318 NZ_CP089001:c1961100-1960955 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References