Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3250822..3250967 Replicon chromosome
Accession NZ_CP088997
Organism Klebsiella pneumoniae strain 49088

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3250829..3250931 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3250822..3250967 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ82_RS16260 (LRZ82_16260) 3246354..3247787 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LRZ82_RS16265 (LRZ82_16265) 3247903..3248142 + 240 WP_002911393.1 YebV family protein -
LRZ82_RS16270 (LRZ82_16270) 3248240..3248431 + 192 WP_002911395.1 YebW family protein -
LRZ82_RS16275 (LRZ82_16275) 3248428..3249081 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
LRZ82_RS16280 (LRZ82_16280) 3249238..3250206 + 969 WP_004151446.1 VirK/YbjX family protein -
LRZ82_RS16285 (LRZ82_16285) 3250311..3250454 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3250822..3250967 + 146 - - Antitoxin
- 3250829..3250931 - 103 - - Toxin
LRZ82_RS16290 (LRZ82_16290) 3251090..3251428 - 339 WP_002911404.1 YebY family protein -
LRZ82_RS16295 (LRZ82_16295) 3251445..3252314 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LRZ82_RS16300 (LRZ82_16300) 3252318..3252692 - 375 WP_004151448.1 CopC domain-containing protein YobA -
LRZ82_RS16305 (LRZ82_16305) 3252805..3253035 + 231 WP_002911406.1 DNA polymerase III subunit theta -
LRZ82_RS16310 (LRZ82_16310) 3253114..3253773 + 660 WP_002911407.1 exodeoxyribonuclease X -
LRZ82_RS16315 (LRZ82_16315) 3253777..3255837 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227292 NZ_CP088997:c3250931-3250829 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227292 NZ_CP088997:3250822-3250967 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References