Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012440..2012585 Replicon chromosome
Accession NZ_CP088991
Organism Klebsiella pneumoniae strain 50700

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012476..2012578 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012440..2012585 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ81_RS09865 (LRZ81_09865) 2007570..2009630 + 2061 WP_004151449.1 oligopeptidase B -
LRZ81_RS09870 (LRZ81_09870) 2009634..2010293 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRZ81_RS09875 (LRZ81_09875) 2010372..2010602 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRZ81_RS09880 (LRZ81_09880) 2010715..2011089 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LRZ81_RS09885 (LRZ81_09885) 2011093..2011962 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LRZ81_RS09890 (LRZ81_09890) 2011979..2012317 + 339 WP_002911404.1 YebY family protein -
- 2012440..2012585 - 146 - - Antitoxin
- 2012476..2012578 + 103 - - Toxin
LRZ81_RS09895 (LRZ81_09895) 2012953..2013096 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LRZ81_RS09900 (LRZ81_09900) 2013201..2014169 - 969 WP_004151446.1 VirK/YbjX family protein -
LRZ81_RS09905 (LRZ81_09905) 2014326..2014979 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LRZ81_RS09910 (LRZ81_09910) 2014976..2015167 - 192 WP_002911395.1 YebW family protein -
LRZ81_RS09915 (LRZ81_09915) 2015265..2015504 - 240 WP_002911393.1 YebV family protein -
LRZ81_RS09920 (LRZ81_09920) 2015620..2017053 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227265 NZ_CP088991:2012476-2012578 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227265 NZ_CP088991:c2012585-2012440 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References