Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2133704..2133849 Replicon chromosome
Accession NZ_CP088988
Organism Klebsiella pneumoniae strain 53322

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2133740..2133842 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2133704..2133849 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ75_RS10115 2128834..2130894 + 2061 WP_004151449.1 oligopeptidase B -
LRZ75_RS10120 2130898..2131557 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRZ75_RS10125 2131636..2131866 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRZ75_RS10130 2131979..2132353 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LRZ75_RS10135 2132357..2133226 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LRZ75_RS10140 2133243..2133581 + 339 WP_002911404.1 YebY family protein -
- 2133704..2133849 - 146 - - Antitoxin
- 2133740..2133842 + 103 - - Toxin
LRZ75_RS10145 2134217..2134360 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LRZ75_RS10150 2134465..2135433 - 969 WP_004151446.1 VirK/YbjX family protein -
LRZ75_RS10155 2135590..2136243 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
LRZ75_RS10160 2136240..2136431 - 192 WP_002911395.1 YebW family protein -
LRZ75_RS10165 2136529..2136768 - 240 WP_002911393.1 YebV family protein -
LRZ75_RS10170 2136884..2138317 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227243 NZ_CP088988:2133740-2133842 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227243 NZ_CP088988:c2133849-2133704 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References