Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1823051..1823196 Replicon chromosome
Accession NZ_CP088985
Organism Klebsiella pneumoniae strain 53334

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1823087..1823189 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1823051..1823196 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ83_RS08805 (LRZ83_08805) 1818181..1820241 + 2061 WP_004151449.1 oligopeptidase B -
LRZ83_RS08810 (LRZ83_08810) 1820245..1820904 - 660 WP_021440386.1 exodeoxyribonuclease X -
LRZ83_RS08815 (LRZ83_08815) 1820983..1821213 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRZ83_RS08820 (LRZ83_08820) 1821326..1821700 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LRZ83_RS08825 (LRZ83_08825) 1821704..1822573 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LRZ83_RS08830 (LRZ83_08830) 1822590..1822928 + 339 WP_016529031.1 YebY family protein -
- 1823051..1823196 - 146 - - Antitoxin
- 1823087..1823189 + 103 - - Toxin
LRZ83_RS08835 (LRZ83_08835) 1823565..1823708 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LRZ83_RS08840 (LRZ83_08840) 1823813..1824781 - 969 WP_004151446.1 VirK/YbjX family protein -
LRZ83_RS08845 (LRZ83_08845) 1824938..1825591 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
LRZ83_RS08850 (LRZ83_08850) 1825588..1825779 - 192 WP_002911395.1 YebW family protein -
LRZ83_RS08855 (LRZ83_08855) 1825877..1826116 - 240 WP_002911393.1 YebV family protein -
LRZ83_RS08860 (LRZ83_08860) 1826232..1827665 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227220 NZ_CP088985:1823087-1823189 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227220 NZ_CP088985:c1823196-1823051 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References