Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2091762..2091907 Replicon chromosome
Accession NZ_CP088982
Organism Klebsiella pneumoniae strain 53357

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2091798..2091900 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2091762..2091907 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRZ78_RS10010 2086892..2088952 + 2061 WP_004151449.1 oligopeptidase B -
LRZ78_RS10015 2088956..2089615 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRZ78_RS10020 2089694..2089924 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRZ78_RS10025 2090037..2090411 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LRZ78_RS10030 2090415..2091284 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
LRZ78_RS10035 2091301..2091639 + 339 WP_002911404.1 YebY family protein -
- 2091762..2091907 - 146 - - Antitoxin
- 2091798..2091900 + 103 - - Toxin
LRZ78_RS10040 2092275..2092418 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LRZ78_RS10045 2092523..2093491 - 969 WP_014907334.1 VirK/YbjX family protein -
LRZ78_RS10050 2093648..2094301 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LRZ78_RS10055 2094298..2094489 - 192 WP_002911395.1 YebW family protein -
LRZ78_RS10060 2094587..2094826 - 240 WP_002911393.1 YebV family protein -
LRZ78_RS10065 2094942..2096375 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227199 NZ_CP088982:2091798-2091900 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227199 NZ_CP088982:c2091907-2091762 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References