Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1924938..1925083 | Replicon | chromosome |
| Accession | NZ_CP088978 | ||
| Organism | Klebsiella pneumoniae strain KP015 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1924974..1925076 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1924938..1925083 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LST75_RS09215 (LST75_09210) | 1920068..1922128 | + | 2061 | WP_040188725.1 | oligopeptidase B | - |
| LST75_RS09220 (LST75_09215) | 1922132..1922791 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| LST75_RS09225 (LST75_09220) | 1922870..1923100 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| LST75_RS09230 (LST75_09225) | 1923213..1923587 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| LST75_RS09235 (LST75_09230) | 1923591..1924460 | + | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| LST75_RS09240 (LST75_09235) | 1924477..1924815 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1924938..1925083 | - | 146 | - | - | Antitoxin |
| - | 1924974..1925076 | + | 103 | - | - | Toxin |
| LST75_RS09245 (LST75_09240) | 1925451..1925594 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| LST75_RS09250 (LST75_09245) | 1925699..1926667 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| LST75_RS09255 (LST75_09250) | 1926824..1927477 | + | 654 | WP_023280291.1 | protein-serine/threonine phosphatase | - |
| LST75_RS09260 (LST75_09255) | 1927474..1927665 | - | 192 | WP_002911395.1 | YebW family protein | - |
| LST75_RS09265 (LST75_09260) | 1927763..1928002 | - | 240 | WP_002911393.1 | YebV family protein | - |
| LST75_RS09270 (LST75_09265) | 1928118..1929551 | - | 1434 | WP_040188727.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T227178 NZ_CP088978:1924974-1925076 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT227178 NZ_CP088978:c1925083-1924938 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT