Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1924938..1925083 Replicon chromosome
Accession NZ_CP088978
Organism Klebsiella pneumoniae strain KP015

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1924974..1925076 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1924938..1925083 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LST75_RS09215 (LST75_09210) 1920068..1922128 + 2061 WP_040188725.1 oligopeptidase B -
LST75_RS09220 (LST75_09215) 1922132..1922791 - 660 WP_002911407.1 exodeoxyribonuclease X -
LST75_RS09225 (LST75_09220) 1922870..1923100 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LST75_RS09230 (LST75_09225) 1923213..1923587 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LST75_RS09235 (LST75_09230) 1923591..1924460 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LST75_RS09240 (LST75_09235) 1924477..1924815 + 339 WP_002911404.1 YebY family protein -
- 1924938..1925083 - 146 - - Antitoxin
- 1924974..1925076 + 103 - - Toxin
LST75_RS09245 (LST75_09240) 1925451..1925594 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LST75_RS09250 (LST75_09245) 1925699..1926667 - 969 WP_004151446.1 VirK/YbjX family protein -
LST75_RS09255 (LST75_09250) 1926824..1927477 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
LST75_RS09260 (LST75_09255) 1927474..1927665 - 192 WP_002911395.1 YebW family protein -
LST75_RS09265 (LST75_09260) 1927763..1928002 - 240 WP_002911393.1 YebV family protein -
LST75_RS09270 (LST75_09265) 1928118..1929551 - 1434 WP_040188727.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227178 NZ_CP088978:1924974-1925076 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227178 NZ_CP088978:c1925083-1924938 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References