Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4585644..4586203 Replicon chromosome
Accession NZ_CP088975
Organism Rhodococcus pyridinivorans strain DNHP-S2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LSF60_RS21590 Protein ID WP_220666559.1
Coordinates 4585644..4585889 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LSF60_RS21595 Protein ID WP_024102980.1
Coordinates 4585919..4586203 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LSF60_RS21560 (LSF60_21560) 4580765..4581484 + 720 WP_230809687.1 2OG-Fe(II) oxygenase -
LSF60_RS21565 (LSF60_21565) 4581521..4582492 - 972 WP_230809686.1 phosphotriesterase-related protein -
LSF60_RS21570 (LSF60_21570) 4582537..4583367 - 831 WP_006551851.1 SDR family oxidoreductase -
LSF60_RS21575 (LSF60_21575) 4583488..4584150 + 663 WP_231781128.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
LSF60_RS21580 (LSF60_21580) 4584300..4585049 + 750 WP_052227314.1 cutinase family protein -
LSF60_RS21585 (LSF60_21585) 4585108..4585587 + 480 WP_006551854.1 MarR family transcriptional regulator -
LSF60_RS21590 (LSF60_21590) 4585644..4585889 - 246 WP_220666559.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LSF60_RS21595 (LSF60_21595) 4585919..4586203 - 285 WP_024102980.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LSF60_RS21600 (LSF60_21600) 4586428..4587246 - 819 WP_230809683.1 family 1 encapsulin nanocompartment shell protein -
LSF60_RS21605 (LSF60_21605) 4587243..4588271 - 1029 WP_024102977.1 Dyp-type peroxidase -
LSF60_RS21610 (LSF60_21610) 4588348..4589949 - 1602 WP_024102976.1 L-lactate permease -
LSF60_RS21615 (LSF60_21615) 4589954..4590382 - 429 WP_230809681.1 HIT family protein -
LSF60_RS21620 (LSF60_21620) 4590379..4591011 - 633 WP_006551862.1 TetR/AcrR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(30-80)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8961.28 Da        Isoelectric Point: 10.3368

>T227175 WP_220666559.1 NZ_CP088975:c4585889-4585644 [Rhodococcus pyridinivorans]
MARSAARAMARSLPEKVATAVYEFVTGPLLENSKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVEVTAISHRADAY
R

Download         Length: 246 bp

>T227175 NZ_CP122758:2694922-2695029 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10494.56 Da        Isoelectric Point: 4.2336

>AT227175 WP_024102980.1 NZ_CP088975:c4586203-4585919 [Rhodococcus pyridinivorans]
MTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVDVQ
ELTQLMRDARSSEE

Download         Length: 285 bp

>AT227175 NZ_CP122758:c2694875-2694809 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References