Detailed information of TA system TA022710

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 101758..102340
• Replicon: plasmid pAQ6
• Accession: NC_010480
• Organism: Synechococcus sp. PCC 7002

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SYNPCC7002_RS15130
• Protein ID: WP_041444097.1
• Coordinates: 101758..102105 (-)
• Length: 116 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: B1XR88
• Locus tag: SYNPCC7002_RS15135
• Protein ID: WP_012308630.1
• Coordinates: 102095..102340 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SYNPCC7002_RS15130	101758..102105	-	348	WP_041444097.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SYNPCC7002_RS15135	102095..102340	-	246	WP_012308630.1	hypothetical protein	Antitoxin
SYNPCC7002_RS15140	102358..105897	-	3540	WP_012308631.1	N-6 DNA methylase	-
SYNPCC7002_RS15145	106015..106800	+	786	WP_012308632.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..124030	124030

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (19-108)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 116 a.a.
• Molecular weight: 13211.22 Da
• Isoelectric Point: 10.2062

>T22710 WP_041444097.1 NC_010480:c102105-101758 [Synechococcus sp. PCC 7002]
MPDKNPIQIETSAVFRRNLRKLGKKYRNIKQDLQPIIEALSQGELPGDQIPGVSYPVFKLRIRNSDVQKGKSGGYRLIYY
LKTDTGIILLTLYTKSERANISPEDIRQIIENYSN

Nucleotide

• Length: 348 bp

>T22710 NC_010480:c102105-101758 [Synechococcus sp. PCC 7002]
ATGCCGGATAAAAACCCAATCCAAATTGAAACATCCGCTGTTTTCCGTCGCAATCTCCGTAAATTAGGCAAGAAATATCG
CAATATCAAGCAAGATCTTCAGCCCATTATCGAAGCTCTTAGCCAAGGCGAGTTACCCGGCGATCAAATTCCCGGCGTGA
GCTATCCTGTTTTTAAACTGAGAATCCGTAATAGTGATGTTCAGAAAGGAAAAAGTGGTGGTTATCGACTAATTTACTAT
CTCAAAACCGATACAGGCATTATTTTATTGACGCTGTACACAAAATCCGAAAGAGCAAATATTTCTCCCGAAGATATCCG
ACAAATCATAGAAAATTATTCAAATTAG

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9126.25 Da
• Isoelectric Point: 3.9650

>AT22710 WP_012308630.1 NC_010480:c102340-102095 [Synechococcus sp. PCC 7002]
MKAQKVMATIDAQGQLTLDDPLVAIKNSRVEVIILIPEEDEADDEPTRAELLDDFRQAWHEAMTGQTLPIEKLWDDIDHA
G

Nucleotide

• Length: 246 bp

>AT22710 NC_010480:c102340-102095 [Synechococcus sp. PCC 7002]
ATGAAAGCACAAAAAGTCATGGCAACCATTGATGCTCAGGGTCAACTTACCCTTGATGATCCTTTAGTTGCGATTAAAAA
TAGCCGTGTCGAAGTCATTATCCTCATTCCCGAAGAAGACGAAGCCGACGACGAACCCACAAGAGCAGAATTACTCGATG
ATTTCCGGCAAGCATGGCATGAAGCAATGACCGGACAAACCCTTCCCATTGAAAAACTTTGGGATGATATCGACCATGCC
GGATAA

Structures

Antitoxin

• AlphaFold DB: B1XR88