Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 921490..922154 Replicon chromosome
Accession NZ_CP088292
Organism Phyllobacterium sp. T1018

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LLE51_RS04425 Protein ID WP_228017291.1
Coordinates 921490..921918 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LLE51_RS04430 Protein ID WP_027230583.1
Coordinates 921915..922154 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLE51_RS04410 (LLE51_004410) 916606..918369 + 1764 WP_228017293.1 hypothetical protein -
LLE51_RS04415 (LLE51_004415) 918366..918788 + 423 WP_091950798.1 hypothetical protein -
LLE51_RS04420 (LLE51_004420) 919048..921489 + 2442 WP_036813457.1 DNA topoisomerase (ATP-hydrolyzing) subunit B -
LLE51_RS04425 (LLE51_004425) 921490..921918 - 429 WP_228017291.1 type II toxin-antitoxin system VapC family toxin Toxin
LLE51_RS04430 (LLE51_004430) 921915..922154 - 240 WP_027230583.1 hypothetical protein Antitoxin
LLE51_RS04435 (LLE51_004435) 922438..923493 + 1056 WP_228017290.1 dipeptidase -
LLE51_RS04440 (LLE51_004440) 923530..925140 + 1611 WP_162737145.1 ABC transporter substrate-binding protein -
LLE51_RS04445 (LLE51_004445) 925163..926230 + 1068 WP_027230580.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15463.74 Da        Isoelectric Point: 5.1832

>T227086 WP_228017291.1 NZ_CP088292:c921918-921490 [Phyllobacterium sp. T1018]
MIVLDTNVISEPLKRSPDPGVLSWLDQQGAETLFLTTTSLSELLLGIELLPKGKRKQGLDRALSELISYLFGDRILDFDR
QAALVYAPLVSQARSTGRTISIADGQIAAVAKSRGYSVASRDTMPFTAAGLTVINPWQEEKT

Download         Length: 429 bp

>T227086 NZ_CP122712:3946471-3946689 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8798.90 Da        Isoelectric Point: 6.7293

>AT227086 WP_027230583.1 NZ_CP088292:c922154-921915 [Phyllobacterium sp. T1018]
MAAVTIRNLPEETHRALKLRAAKHGRSTEAEIREILEEATRPKDRLKIGSELAAFGRRHGGLDLEPGRDQTPAEPADFE

Download         Length: 240 bp

>AT227086 NZ_CP122712:3946071-3946445 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References