Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1798120..1798721 Replicon chromosome
Accession NZ_CP088288
Organism Bradyrhizobium septentrionale strain 162S2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HU675_RS08480 Protein ID WP_176540663.1
Coordinates 1798425..1798721 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HU675_RS08475 Protein ID WP_166213639.1
Coordinates 1798120..1798428 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HU675_RS08455 (HU675_0008455) 1794553..1795611 + 1059 WP_166213643.1 polysaccharide deacetylase family protein -
HU675_RS08460 (HU675_0008460) 1795686..1796411 - 726 WP_166213642.1 sulfite exporter TauE/SafE family protein -
HU675_RS08465 (HU675_0008465) 1796584..1796853 + 270 WP_166213641.1 hypothetical protein -
HU675_RS08470 (HU675_0008470) 1797105..1797905 + 801 WP_166213640.1 SDR family oxidoreductase -
HU675_RS08475 (HU675_0008475) 1798120..1798428 + 309 WP_166213639.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HU675_RS08480 (HU675_0008480) 1798425..1798721 + 297 WP_176540663.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HU675_RS08485 (HU675_0008485) 1798770..1799609 - 840 WP_166213637.1 alpha/beta hydrolase -
HU675_RS08490 (HU675_0008490) 1799733..1801169 - 1437 WP_166216529.1 benzoyl-CoA 2,3-epoxidase subunit BoxB -
HU675_RS08495 (HU675_0008495) 1801327..1803015 - 1689 WP_166213636.1 2,3-epoxybenzoyl-CoA dihydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-52)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11084.46 Da        Isoelectric Point: 4.6556

>T227079 WP_176540663.1 NZ_CP088288:1798425-1798721 [Bradyrhizobium septentrionale]
MKLVWSRFALSDRDDIFSYIEAENPRAAVHVDEQIADAARRLLDFPDSGRPGRVAGTRELVIPRTPYIAAYLVDGETGRI
LRVLHGAQMWTDELTNDD

Download         Length: 297 bp

>T227079 NZ_CP122712:c2261966-2261859 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11262.69 Da        Isoelectric Point: 7.2053

>AT227079 WP_166213639.1 NZ_CP088288:1798120-1798428 [Bradyrhizobium septentrionale]
MASNALVQTRIDADVKEKATAVLENMGLTVSDAVRILLTRTANEGALPLELVSNSQAYDSWFGEKVRHALADTRPNLDDS
EVEAHFAQRRTAALRKAAERKR

Download         Length: 309 bp

>AT227079 NZ_CP122712:2262013-2262079 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References