Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 2106043..2106644 Replicon chromosome
Accession NZ_CP088285
Organism Bradyrhizobium septentrionale strain 1S1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HAP48_RS11920 Protein ID WP_166213638.1
Coordinates 2106348..2106644 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HAP48_RS11915 Protein ID WP_166213639.1
Coordinates 2106043..2106351 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HAP48_RS11895 (HAP48_0011895) 2102476..2103534 + 1059 WP_166213643.1 polysaccharide deacetylase family protein -
HAP48_RS11900 (HAP48_0011900) 2103609..2104334 - 726 WP_166213642.1 sulfite exporter TauE/SafE family protein -
HAP48_RS11905 (HAP48_0011905) 2104507..2104776 + 270 WP_166213641.1 hypothetical protein -
HAP48_RS11910 (HAP48_0011910) 2105028..2105828 + 801 WP_166213640.1 SDR family oxidoreductase -
HAP48_RS11915 (HAP48_0011915) 2106043..2106351 + 309 WP_166213639.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HAP48_RS11920 (HAP48_0011920) 2106348..2106644 + 297 WP_166213638.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HAP48_RS11925 (HAP48_0011925) 2106693..2107532 - 840 WP_166213637.1 alpha/beta hydrolase -
HAP48_RS11930 (HAP48_0011930) 2107656..2109092 - 1437 WP_166216529.1 benzoyl-CoA 2,3-epoxidase subunit BoxB -
HAP48_RS11935 (HAP48_0011935) 2109250..2110938 - 1689 WP_166213636.1 2,3-epoxybenzoyl-CoA dihydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-52)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11080.47 Da        Isoelectric Point: 4.6556

>T227077 WP_166213638.1 NZ_CP088285:2106348-2106644 [Bradyrhizobium septentrionale]
MKLVWSRFALSDRDDIFSYIEAENPRAAVHVDEQIADAARRLLDFPDSGRPGRVAGTRELVIPRTPYIAAYLVDGETGRI
LRVLHGAQMWPDELTNDD

Download         Length: 297 bp

>T227077 NZ_CP122712:2071151-2071405 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11262.69 Da        Isoelectric Point: 7.2053

>AT227077 WP_166213639.1 NZ_CP088285:2106043-2106351 [Bradyrhizobium septentrionale]
MASNALVQTRIDADVKEKATAVLENMGLTVSDAVRILLTRTANEGALPLELVSNSQAYDSWFGEKVRHALADTRPNLDDS
EVEAHFAQRRTAALRKAAERKR

Download         Length: 309 bp

>AT227077 NZ_CP122712:2070903-2071154 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References