Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 2922767..2924052 | Replicon | chromosome |
| Accession | NZ_CP088280 | ||
| Organism | Bradyrhizobium barranii subsp. barranii strain 323S2 | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | - |
| Locus tag | G6321_RS17205 | Protein ID | WP_256461632.1 |
| Coordinates | 2922767..2922991 (+) | Length | 75 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | - |
| Locus tag | G6321_RS17210 | Protein ID | WP_166342570.1 |
| Coordinates | 2922991..2924052 (+) | Length | 354 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G6321_RS17175 (G6321_00017175) | 2918202..2919545 | + | 1344 | WP_018272321.1 | IS1380-like element ISBdi2 family transposase | - |
| G6321_RS17180 (G6321_00017180) | 2919754..2920338 | + | 585 | WP_224517363.1 | hypothetical protein | - |
| G6321_RS17185 (G6321_00017185) | 2920454..2920801 | - | 348 | Protein_2753 | SOS response-associated peptidase family protein | - |
| G6321_RS17190 (G6321_00017190) | 2920978..2921406 | + | 429 | WP_166353255.1 | DUF4433 domain-containing protein | - |
| G6321_RS17195 (G6321_00017195) | 2921297..2921650 | - | 354 | WP_224517876.1 | hypothetical protein | - |
| G6321_RS17200 (G6321_00017200) | 2921534..2922732 | + | 1199 | Protein_2756 | IS256 family transposase | - |
| G6321_RS17205 (G6321_00017205) | 2922767..2922991 | + | 225 | WP_256461632.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | Toxin |
| G6321_RS17210 (G6321_00017210) | 2922991..2924052 | + | 1062 | WP_166342570.1 | macro domain-containing protein | Antitoxin |
| G6321_RS17215 (G6321_00017215) | 2924284..2924763 | - | 480 | WP_166342569.1 | hypothetical protein | - |
| G6321_RS17220 (G6321_00017220) | 2924776..2925864 | - | 1089 | WP_207794559.1 | ImmA/IrrE family metallo-endopeptidase | - |
| G6321_RS17225 (G6321_00017225) | 2926087..2927463 | - | 1377 | WP_166342567.1 | site-specific integrase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2905565..2927463 | 21898 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 75 a.a. Molecular weight: 8701.86 Da Isoelectric Point: 6.4472
>T227070 WP_256461632.1 NZ_CP088280:2922767-2922991 [Bradyrhizobium barranii subsp. barranii]
IDWEMLQRRDFKNDPEDPSKKERYQAEALVHKHMPMASLFGFACYNDACVQTIQNALASRKMTADVVNKSDWYF
IDWEMLQRRDFKNDPEDPSKKERYQAEALVHKHMPMASLFGFACYNDACVQTIQNALASRKMTADVVNKSDWYF
Download Length: 225 bp
>T227070 NZ_CP122712:666796-667110 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
Antitoxin
Download Length: 354 a.a. Molecular weight: 39779.14 Da Isoelectric Point: 8.2215
>AT227070 WP_166342570.1 NZ_CP088280:2922991-2924052 [Bradyrhizobium barranii subsp. barranii]
MIEFTRGNLLDAKVDALVNTVNTVGVMGKGVALMFKEAFPENFKDYEAACKKKAVKVGKMFVTKRLLSPKWIINFPTKEH
WRGDSKLEWIETGLEDLKRVIIENGIESIAIPPLGSGNGGLKWEDVRPKIEAALSSLKDVTVFVYEPTDQYQNVAKRSGV
EQLTPARALVAELVRRYWILGIECSLLEIQKLAYFLERSIEILKVKNPLDLRFQADKYGPYAPRLTHLLDGLDGSYLHCG
KRIGDASPFDVIWFEDSKRDKVAAYLRSGEAKAYLPALENTAKLIDGFESPLGVELLATVDWLVHKDGIKLEREAVKVAL
KTWTGGEKSSERKLKLFEDRLIDLALERLHSFG
MIEFTRGNLLDAKVDALVNTVNTVGVMGKGVALMFKEAFPENFKDYEAACKKKAVKVGKMFVTKRLLSPKWIINFPTKEH
WRGDSKLEWIETGLEDLKRVIIENGIESIAIPPLGSGNGGLKWEDVRPKIEAALSSLKDVTVFVYEPTDQYQNVAKRSGV
EQLTPARALVAELVRRYWILGIECSLLEIQKLAYFLERSIEILKVKNPLDLRFQADKYGPYAPRLTHLLDGLDGSYLHCG
KRIGDASPFDVIWFEDSKRDKVAAYLRSGEAKAYLPALENTAKLIDGFESPLGVELLATVDWLVHKDGIKLEREAVKVAL
KTWTGGEKSSERKLKLFEDRLIDLALERLHSFG
Download Length: 1062 bp
>AT227070 NZ_CP122712:667107-667523 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|