Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2004070..2004215 Replicon chromosome
Accession NZ_CP088269
Organism Klebsiella pneumoniae strain CRKP-27

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2004106..2004208 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2004070..2004215 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ775_RS09575 1999200..2001260 + 2061 WP_004151449.1 oligopeptidase B -
LQ775_RS09580 2001264..2001923 - 660 WP_002911407.1 exodeoxyribonuclease X -
LQ775_RS09585 2002002..2002232 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LQ775_RS09590 2002345..2002719 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LQ775_RS09595 2002723..2003592 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
LQ775_RS09600 2003609..2003947 + 339 WP_002911404.1 YebY family protein -
- 2004070..2004215 - 146 - - Antitoxin
- 2004106..2004208 + 103 - - Toxin
LQ775_RS09605 2004583..2004726 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LQ775_RS09610 2004831..2005799 - 969 WP_014907334.1 VirK/YbjX family protein -
LQ775_RS09615 2005956..2006609 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
LQ775_RS09620 2006606..2006797 - 192 WP_002911395.1 YebW family protein -
LQ775_RS09625 2006895..2007134 - 240 WP_002911393.1 YebV family protein -
LQ775_RS09630 2007250..2008683 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T227038 NZ_CP088269:2004106-2004208 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT227038 NZ_CP088269:c2004215-2004070 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References