Detailed information of TA system TA227011

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 1838476..1838995
• Replicon: chromosome
• Accession: NZ_CP088252
• Organism: Frateuria soli strain 5GH9-11

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LQ771_RS08465
• Protein ID: WP_231348975.1
• Coordinates: 1838476..1838760 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LQ771_RS08470
• Protein ID: WP_231348976.1
• Coordinates: 1838750..1838995 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ771_RS08450 (LQ771_08450)	1834651..1834950	-	300	WP_231348972.1	type II toxin-antitoxin system RelE/ParE family toxin	-
LQ771_RS08455 (LQ771_08455)	1834947..1835219	-	273	WP_231348973.1	YlcI/YnfO family protein	-
LQ771_RS08460 (LQ771_08460)	1835295..1838393	-	3099	WP_231348974.1	type I restriction endonuclease	-
LQ771_RS08465 (LQ771_08465)	1838476..1838760	-	285	WP_231348975.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
LQ771_RS08470 (LQ771_08470)	1838750..1838995	-	246	WP_231348976.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LQ771_RS08475 (LQ771_08475)	1839089..1840759	-	1671	WP_231348977.1	urocanate hydratase	-
LQ771_RS08480 (LQ771_08480)	1840908..1842230	+	1323	WP_231348978.1	hypothetical protein	-
LQ771_RS08485 (LQ771_08485)	1842386..1843768	-	1383	WP_231348979.1	class II fumarate hydratase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-72)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10811.89 Da
• Isoelectric Point: 10.7434

>T227011 WP_231348975.1 NZ_CP088252:c1838760-1838476 [Frateuria soli]
MTYSLEFVESALKEWRKLSPDIRAQLKKKLAERLEHPHVPAARLHGMPDCFKIKLRASGYRLVYQVHDKVLVVTVVAVGK
REKGLTYLAAKKRV

Nucleotide

• Length: 285 bp

>T227011 NZ_CP122679:1998560-1998814 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAGTCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 8983.39 Da
• Isoelectric Point: 5.8650

>AT227011 WP_231348976.1 NZ_CP088252:c1838995-1838750 [Frateuria soli]
MEAILAGASISITELKRNPSAVIEAADGESVAVLVHNKPSAYLVPAETYKRLLDRLEDLELAELVRQRKGERRVKVKLDD
L

Nucleotide

• Length: 246 bp

>AT227011 NZ_CP122679:1998312-1998563 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCTGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA