Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2823576..2823721 Replicon chromosome
Accession NZ_CP088229
Organism Enterobacter kobei strain Ek72

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2823583..2823686 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2823576..2823721 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LK774_RS13550 (LK774_13575) 2818650..2819261 + 612 WP_063308740.1 hypothetical protein -
LK774_RS13555 (LK774_13580) 2819258..2819449 + 192 WP_022650956.1 DUF1382 family protein -
LK774_RS13560 (LK774_13585) 2819446..2819766 + 321 WP_063308741.1 hypothetical protein -
LK774_RS13565 (LK774_13590) 2819858..2820283 + 426 WP_063308742.1 hypothetical protein -
LK774_RS13570 (LK774_13595) 2820285..2820503 + 219 WP_213833319.1 TraR/DksA family transcriptional regulator -
LK774_RS13575 (LK774_13600) 2820503..2820958 + 456 WP_045346710.1 hypothetical protein -
LK774_RS13580 (LK774_13605) 2820921..2821160 + 240 WP_045346711.1 DUF4222 domain-containing protein -
LK774_RS13585 (LK774_13610) 2821170..2821481 + 312 WP_045346712.1 hypothetical protein -
LK774_RS13590 (LK774_13615) 2821585..2821962 + 378 WP_045281533.1 hypothetical protein -
LK774_RS13595 (LK774_13620) 2822179..2822451 + 273 WP_023330710.1 excisionase -
LK774_RS13600 (LK774_13625) 2822420..2823505 + 1086 WP_023330711.1 phage integrase Arm DNA-binding domain-containing protein -
- 2823576..2823721 + 146 - - Antitoxin
- 2823583..2823686 - 104 - - Toxin
LK774_RS13605 (LK774_13630) 2823825..2824163 - 339 WP_014884299.1 YebY family protein -
LK774_RS13610 (LK774_13635) 2824180..2825049 - 870 WP_023330712.1 copper homeostasis membrane protein CopD -
LK774_RS13615 (LK774_13640) 2825051..2825422 - 372 WP_023330713.1 CopC domain-containing protein YobA -
LK774_RS13620 (LK774_13645) 2825560..2825790 + 231 WP_013096102.1 DNA polymerase III subunit theta -
LK774_RS13625 (LK774_13650) 2825901..2826551 + 651 WP_014884302.1 carbon-nitrogen hydrolase family protein -
LK774_RS13630 (LK774_13655) 2826576..2827238 + 663 WP_014884303.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2786696..2845271 58575


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T226988 NZ_CP088229:c2823686-2823583 [Enterobacter kobei]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT226988 NZ_CP088229:2823576-2823721 [Enterobacter kobei]
AATAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References