Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 462375..462970 Replicon chromosome
Accession NZ_CP088229
Organism Enterobacter kobei strain Ek72

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag LK774_RS02190 Protein ID WP_023331877.1
Coordinates 462620..462970 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag LK774_RS02185 Protein ID WP_023331876.1
Coordinates 462375..462626 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LK774_RS02175 (LK774_02180) 458042..461818 + 3777 WP_023331875.1 autotransporter assembly complex protein TamB -
LK774_RS02180 (LK774_02185) 461821..462165 + 345 WP_014882267.1 gamma-glutamylcyclotransferase -
LK774_RS02185 (LK774_02190) 462375..462626 + 252 WP_023331876.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LK774_RS02190 (LK774_02195) 462620..462970 + 351 WP_023331877.1 type II toxin-antitoxin system ChpB family toxin Toxin
LK774_RS02195 (LK774_02200) 463048..463578 - 531 WP_008501423.1 inorganic diphosphatase -
LK774_RS02200 (LK774_02205) 463888..464844 + 957 WP_014882271.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
LK774_RS02205 (LK774_02210) 464976..466478 + 1503 WP_023331878.1 sugar ABC transporter ATP-binding protein -
LK774_RS02210 (LK774_02215) 466489..467514 + 1026 WP_014882273.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-115)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12339.36 Da        Isoelectric Point: 6.9493

>T226984 WP_023331877.1 NZ_CP088229:462620-462970 [Enterobacter kobei]
MVKRPCFERGDIVLVGFDPANGHEQKGAGRPALVLSVSAFNQLGMTLVAPVTQGGNFARYAGFSVPLSCEEGNILGVILV
NQIRMMDLGARLAKRIGVASDETVEDALLRLQAILS

Download         Length: 351 bp

>T226984 NZ_CP122674:c94813-94661 [Escherichia coli]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9074.44 Da        Isoelectric Point: 4.2517

>AT226984 WP_023331876.1 NZ_CP088229:462375-462626 [Enterobacter kobei]
MRITIKKWGNSAGMVIPGVVMKELGLKPGQSMEAQVTNNQLVLTPVSKQYSLEELLAQCDMSAPEINEQDVWGTSGPIGD
EVW

Download         Length: 252 bp

>AT226984 NZ_CP122674:94868-94925 [Escherichia coli]
GCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References