Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TscAT/- |
Location | 864154..864686 | Replicon | chromosome |
Accession | NZ_CP088158 | ||
Organism | Staphylococcus aureus strain 697 |
Toxin (Protein)
Gene name | TscT | Uniprot ID | Q93CD4 |
Locus tag | LRP64_RS04100 | Protein ID | WP_001103942.1 |
Coordinates | 864366..864686 (+) | Length | 107 a.a. |
Antitoxin (Protein)
Gene name | TscA | Uniprot ID | - |
Locus tag | LRP64_RS04095 | Protein ID | WP_001058486.1 |
Coordinates | 864154..864363 (+) | Length | 70 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LRP64_RS04050 (859172) | 859172..860392 | - | 1221 | WP_000266157.1 | site-specific integrase | - |
LRP64_RS04055 (860481) | 860481..861209 | - | 729 | WP_000733774.1 | staphylococcal enterotoxin type K | - |
LRP64_RS04060 (861233) | 861233..861961 | - | 729 | WP_001033316.1 | staphylococcal enterotoxin type Q | - |
LRP64_RS04065 (862032) | 862032..862463 | - | 432 | WP_001228759.1 | hypothetical protein | - |
LRP64_RS04070 (862480) | 862480..862938 | - | 459 | WP_000281657.1 | ImmA/IrrE family metallo-endopeptidase | - |
LRP64_RS04075 (862950) | 862950..863282 | - | 333 | WP_001260004.1 | helix-turn-helix transcriptional regulator | - |
LRP64_RS04080 (863475) | 863475..863738 | + | 264 | WP_000243851.1 | helix-turn-helix transcriptional regulator | - |
LRP64_RS04085 (863731) | 863731..864003 | + | 273 | WP_000091731.1 | helix-turn-helix domain-containing protein | - |
LRP64_RS04090 (864015) | 864015..864161 | + | 147 | WP_000784875.1 | hypothetical protein | - |
LRP64_RS04095 (864154) | 864154..864363 | + | 210 | WP_001058486.1 | hypothetical protein | Antitoxin |
LRP64_RS04100 (864366) | 864366..864686 | + | 321 | WP_001103942.1 | DUF1474 family protein | Toxin |
LRP64_RS04105 (864750) | 864750..865619 | + | 870 | WP_001002732.1 | primase alpha helix C-terminal domain-containing protein | - |
LRP64_RS04110 (865636) | 865636..867105 | + | 1470 | WP_000390454.1 | virulence-associated E family protein | - |
LRP64_RS04115 (867391) | 867391..867753 | + | 363 | WP_001039168.1 | hypothetical protein | - |
LRP64_RS04120 (867755) | 867755..868039 | + | 285 | WP_240696975.1 | pathogenicity island protein | - |
LRP64_RS04125 (868036) | 868036..868677 | + | 642 | WP_001019764.1 | hypothetical protein | - |
LRP64_RS04130 (869194) | 869194..869535 | + | 342 | WP_001190615.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | selk / selq / seb | 855931..874486 | 18555 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 107 a.a. Molecular weight: 12694.22 Da Isoelectric Point: 4.7419
>T226881 WP_001103942.1 NZ_CP088158:864366-864686 [Staphylococcus aureus]
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFSELIQKF
HEIEKASSENFDEESDDAKNSIKVAE
MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKREHINFSASYLEHRIQNEHTVELLHVYLKEFSELIQKF
HEIEKASSENFDEESDDAKNSIKVAE
Download Length: 321 bp
>T226881 NZ_CP122648:2907096-2907203 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTTGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTTGCGTAACCGGAAGTAA
Antitoxin
Download Length: 70 a.a. Molecular weight: 8252.31 Da Isoelectric Point: 4.3718
>AT226881 WP_001058486.1 NZ_CP088158:864154-864363 [Staphylococcus aureus]
MNNEQKEVIEHLVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
MNNEQKEVIEHLVYQLELSVMNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
Download Length: 210 bp
>AT226881 NZ_CP122648:c2907049-2906983 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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