Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2011661..2011932 | Replicon | chromosome |
| Accession | NC_010473 | ||
| Organism | Escherichia coli str. K-12 substr. DH10B | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2011699..2011802 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2011661..2011932 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ECDH10B_RS10115 (ECDH10B_1974) | 2008818..2010257 | + | 1440 | WP_001352260.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| ECDH10B_RS10120 (ECDH10B_1975) | 2010375..2010611 | + | 237 | WP_001295499.1 | DUF1480 family protein | - |
| ECDH10B_RS10125 (ECDH10B_1976) | 2010716..2010907 | + | 192 | WP_000457842.1 | YebW family protein | - |
| ECDH10B_RS10130 (ECDH10B_1977) | 2010908..2011564 | - | 657 | WP_000812724.1 | protein-serine/threonine phosphatase | - |
| - | 2011661..2011932 | + | 272 | - | - | Antitoxin |
| - | 2011699..2011802 | - | 104 | - | - | Toxin |
| ECDH10B_RS10140 (ECDH10B_1980) | 2011960..2012301 | - | 342 | WP_000976476.1 | YebY family protein | - |
| ECDH10B_RS10145 (ECDH10B_1981) | 2012314..2013186 | - | 873 | WP_000879289.1 | copper homeostasis membrane protein CopD | - |
| ECDH10B_RS10150 (ECDH10B_1982) | 2013190..2013564 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| ECDH10B_RS10155 (ECDH10B_1983) | 2013703..2013933 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| ECDH10B_RS10160 (ECDH10B_1984) | 2014035..2014691 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| ECDH10B_RS10165 (ECDH10B_1985) | 2014715..2015377 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T22687 NC_010473:c2011802-2011699 [Escherichia coli str. K-12 substr. DH10B]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT22687 NC_010473:2011661-2011932 [Escherichia coli str. K-12 substr. DH10B]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
