Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 5974635..5975502 Replicon chromosome
Accession NZ_CP088151
Organism Mesorhizobium mediterraneum strain R31

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LRP31_RS29230 Protein ID WP_095486181.1
Coordinates 5974635..5975141 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LRP31_RS29235 Protein ID WP_095486182.1
Coordinates 5975134..5975502 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRP31_RS29215 (LRP31_29100) 5971145..5972026 - 882 WP_095486229.1 cytochrome c oxidase subunit II -
LRP31_RS29220 (LRP31_29105) 5972390..5972944 + 555 WP_095486179.1 invasion associated locus B family protein -
LRP31_RS29225 (LRP31_29110) 5973183..5974595 + 1413 WP_095486180.1 metalloprotease TldD -
LRP31_RS29230 (LRP31_29115) 5974635..5975141 - 507 WP_095486181.1 RES domain-containing protein Toxin
LRP31_RS29235 (LRP31_29120) 5975134..5975502 - 369 WP_095486182.1 DUF2384 domain-containing protein Antitoxin
LRP31_RS29240 (LRP31_29125) 5975600..5976841 - 1242 WP_095486183.1 class I SAM-dependent RNA methyltransferase -
LRP31_RS29245 (LRP31_29130) 5976838..5977632 - 795 WP_095486184.1 TlyA family RNA methyltransferase -
LRP31_RS29250 (LRP31_29135) 5977804..5978205 + 402 WP_095486230.1 GFA family protein -
LRP31_RS29255 (LRP31_29140) 5978344..5980284 - 1941 WP_206072966.1 1-deoxy-D-xylulose-5-phosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(8-161)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(70-119)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18856.37 Da        Isoelectric Point: 5.9155

>T226855 WP_095486181.1 NZ_CP088151:c5975141-5974635 [Mesorhizobium mediterraneum]
MPETRLSLWRAFVPRWAHLPLSGEGAARFGGRWNPLGAPTIYAARELSTAWAEYNQGFVQHPALIAQLELSGARLADLTD
ADTLTELEATTDIHRCEWRDILDRGLVPETHRLRDRLLADGLHGVIYPSFMSPGGTCVALWRWNEDDAPRLGVIDPDHRL
PKTPASWL

Download         Length: 507 bp

>T226855 NZ_CP122643:2526545-2526832 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13004.12 Da        Isoelectric Point: 10.2186

>AT226855 WP_095486182.1 NZ_CP088151:c5975502-5975134 [Mesorhizobium mediterraneum]
MAVALDVPASRFGEERTPFLSARRVAELLGVNLTELAGLIGVARNTLAAKAGARKVDAALSPVVRILAMAGEMAGNEQRA
AIWFKHQPIPGWAGKTAYDLVREGKTDKVLAYLEAVRSGIYA

Download         Length: 369 bp

>AT226855 NZ_CP122643:2526306-2526545 [Escherichia coli]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGTGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References