Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 297775..298406 Replicon chromosome
Accession NZ_CP088150
Organism Bradyrhizobium sp. C-145

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LRP30_RS01395 Protein ID WP_091897895.1
Coordinates 298002..298406 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LRP30_RS01390 Protein ID WP_091897901.1
Coordinates 297775..298005 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRP30_RS01370 (LRP30_01370) 293331..294023 - 693 WP_249759101.1 hypothetical protein -
LRP30_RS01375 (LRP30_01375) 294200..295255 + 1056 WP_249759102.1 LysM peptidoglycan-binding domain-containing protein -
LRP30_RS01380 (LRP30_01380) 295438..296706 + 1269 WP_249761980.1 Spy/CpxP family protein refolding chaperone -
LRP30_RS01385 (LRP30_01385) 296707..297534 - 828 WP_249759103.1 hypothetical protein -
LRP30_RS01390 (LRP30_01390) 297775..298005 + 231 WP_091897901.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LRP30_RS01395 (LRP30_01395) 298002..298406 + 405 WP_091897895.1 PIN domain-containing protein Toxin
LRP30_RS01400 (LRP30_01400) 298577..301024 - 2448 WP_249759104.1 adenylate/guanylate cyclase domain-containing protein -
LRP30_RS01405 (LRP30_01405) 301232..303283 - 2052 WP_249759105.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

SpoVT-AbrB domain

(5-36)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14420.43 Da        Isoelectric Point: 6.8679

>T226850 WP_091897895.1 NZ_CP088150:298002-298406 [Bradyrhizobium sp. C-145]
VSAFFDSNILIYAYSTDTKRQRALNTIAGGGVISAQVLNEFTNVLRKKQKQDWPMIEAAVQSLRFRFPDILPLTSHTHAA
ALALASGHTLAFYDALIVAAAVEAGCDTLYSEDLQHGRSIGGLTIVNPFLGSAP

Download         Length: 405 bp

>T226850 NZ_CP122643:915516-915923 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATCTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATCCACGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCCTGTTGATGGACGGGCGTTTGCGCTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8625.83 Da        Isoelectric Point: 5.1369

>AT226850 WP_091897901.1 NZ_CP088150:297775-298005 [Bradyrhizobium sp. C-145]
VLVSKWGNSLAVRLPKALVEALNLSPGDELNVVEASKGRLAVEKIDKRAEFLRQVEQFQFPLPEGYKFDRDEANER

Download         Length: 231 bp

>AT226850 NZ_CP122643:915269-915535 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAGTGTGACGATCCCGATC
TGTTTAACTGGCTGATGAACCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References