Detailed information of TA system TA226848

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 472308..472827
• Replicon: chromosome
• Accession: NZ_CP088149
• Organism: Pseudomonas sp. S06B 330

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CX511_RS02210
• Protein ID: WP_101293397.1
• Coordinates: 472537..472827 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CX511_RS02205
• Protein ID: WP_045180850.1
• Coordinates: 472308..472547 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CX511_RS02170	468222..468422	-	201	WP_045180856.1	hypothetical protein	-
CX511_RS02175	468797..469117	+	321	WP_220639097.1	DUF3077 domain-containing protein	-
CX511_RS02180	469152..469370	+	219	WP_269216852.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
CX511_RS02185	469495..469989	+	495	WP_101291788.1	type VI secretion system tube protein Hcp	-
CX511_RS02190	470001..470846	+	846	WP_101291787.1	hypothetical protein	-
CX511_RS02195	470857..471228	+	372	WP_101291786.1	hypothetical protein	-
CX511_RS02200	471764..472084	+	321	WP_045180853.1	DUF3077 domain-containing protein	-
CX511_RS02205	472308..472547	+	240	WP_045180850.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
CX511_RS02210	472537..472827	+	291	WP_101293397.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CX511_RS02220	473123..473365	-	243	WP_101293396.1	hypothetical protein	-
CX511_RS02225	473834..474193	+	360	WP_101293395.1	multidrug/spermidine efflux SMR transporter subunit MdtJ	-
CX511_RS02230	474187..474516	+	330	WP_045180834.1	multidrug/spermidine efflux SMR transporter subunit MdtI	-
CX511_RS02235	474758..475975	-	1218	WP_045180831.1	methyltransferase	-
CX511_RS02240	476021..476710	-	690	WP_045180828.1	ABC transporter permease	-
CX511_RS02245	476707..477363	-	657	WP_045180825.1	ABC transporter permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-76)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-68)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11426.26 Da
• Isoelectric Point: 9.9160

>T226848 WP_101293397.1 NZ_CP088149:472537-472827 [Pseudomonas sp. S06B 330]
MTYSLEFDARALKEWHKLGDTVRQQFKKKLTAVLLNPRIEANRLHSLPDCYKIKLRSSGYRLVYQVIDQEIVVFVVAVDK
WEREQVYRKAAERLSE

Nucleotide

• Length: 291 bp

>T226848 NZ_CP122643:c611112-610648 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATAGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCTTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCGATTGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8995.43 Da
• Isoelectric Point: 5.1351

>AT226848 WP_045180850.1 NZ_CP088149:472308-472547 [Pseudomonas sp. S06B 330]
MASINVRIDDDLKARAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALLAKVRERLAAPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT226848 NZ_CP122643:c611447-611112 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA