226672

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1917784..1917929 Replicon chromosome
Accession NZ_CP088120
Organism Klebsiella pneumoniae strain 46

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1917820..1917922 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1917784..1917929 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRM33_RS09355 (LRM33_09355) 1912914..1914974 + 2061 WP_004151449.1 oligopeptidase B -
LRM33_RS09360 (LRM33_09360) 1914978..1915637 - 660 WP_002911407.1 exodeoxyribonuclease X -
LRM33_RS09365 (LRM33_09365) 1915716..1915946 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LRM33_RS09370 (LRM33_09370) 1916059..1916433 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LRM33_RS09375 (LRM33_09375) 1916437..1917306 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LRM33_RS09380 (LRM33_09380) 1917323..1917661 + 339 WP_004189269.1 YebY family protein -
- 1917784..1917929 - 146 - - Antitoxin
- 1917820..1917922 + 103 - - Toxin
LRM33_RS09385 (LRM33_09385) 1918296..1918439 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LRM33_RS09390 (LRM33_09390) 1918544..1919512 - 969 WP_168786284.1 VirK/YbjX family protein -
LRM33_RS09395 (LRM33_09395) 1919669..1920322 + 654 WP_071570906.1 protein-serine/threonine phosphatase -
LRM33_RS09400 (LRM33_09400) 1920319..1920510 - 192 WP_002911395.1 YebW family protein -
LRM33_RS09405 (LRM33_09405) 1920608..1920847 - 240 WP_002911393.1 YebV family protein -
LRM33_RS09410 (LRM33_09410) 1920963..1922396 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T226672 NZ_CP088120:1917820-1917922 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT226672 NZ_CP088120:c1917929-1917784 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References