Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 497218..497813 Replicon chromosome
Accession NZ_CP088119
Organism Enterobacter kobei strain 6

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag LRM31_RS02380 Protein ID WP_032637645.1
Coordinates 497463..497813 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag LRM31_RS02375 Protein ID WP_047027141.1
Coordinates 497218..497469 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRM31_RS02365 (LRM31_02365) 492885..496661 + 3777 WP_047027140.1 autotransporter assembly complex protein TamB -
LRM31_RS02370 (LRM31_02370) 496664..497008 + 345 WP_014882267.1 gamma-glutamylcyclotransferase -
LRM31_RS02375 (LRM31_02375) 497218..497469 + 252 WP_047027141.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LRM31_RS02380 (LRM31_02380) 497463..497813 + 351 WP_032637645.1 type II toxin-antitoxin system ChpB family toxin Toxin
LRM31_RS02385 (LRM31_02385) 497891..498421 - 531 WP_008501423.1 inorganic diphosphatase -
LRM31_RS02390 (LRM31_02390) 498731..499687 + 957 WP_014882271.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
LRM31_RS02395 (LRM31_02395) 499790..501292 + 1503 WP_045134407.1 sugar ABC transporter ATP-binding protein -
LRM31_RS02400 (LRM31_02400) 501303..502328 + 1026 WP_014882273.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12354.33 Da        Isoelectric Point: 6.9493

>T226652 WP_032637645.1 NZ_CP088119:497463-497813 [Enterobacter kobei]
MVKRPCFERGDIVLVGFDPANGHEQKGAGRPALVLSVSAFNQLGMTLVAPVTQGGNFARYAGFSVPLSCEEGNIQGVILV
NQIRMMDLGARLAKRIGVASDETVEDALLRLQAILS

Download         Length: 351 bp

>T226652 NZ_CP122588:2804156-2804263 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9060.41 Da        Isoelectric Point: 4.2517

>AT226652 WP_047027141.1 NZ_CP088119:497218-497469 [Enterobacter kobei]
MRITIKKWGNSAGMVIPGVVMKELGLKPGQSMEAQVTNNQLVLTPVSKQYSLEELLAQCDMSAPEINEQDVWGTSGPVGD
EVW

Download         Length: 252 bp

>AT226652 NZ_CP122588:c2804103-2804042 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References