Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 654822..655357 Replicon plasmid pTA1_1
Accession NZ_CP088105
Organism Rhizobium ruizarguesonis strain TA1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RlegTA1_RS27840 Protein ID WP_027688291.1
Coordinates 655082..655357 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I2GF38
Locus tag RlegTA1_RS27835 Protein ID WP_027688292.1
Coordinates 654822..655082 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RlegTA1_RS27815 (RlegTA1_27815) 650617..651498 - 882 WP_003549874.1 ABC transporter permease -
RlegTA1_RS27820 (RlegTA1_27820) 651510..652328 - 819 WP_026170969.1 ABC transporter ATP-binding protein -
RlegTA1_RS27825 (RlegTA1_27825) 652423..653436 - 1014 WP_018072979.1 ABC transporter substrate-binding protein -
RlegTA1_RS27830 (RlegTA1_27830) 653790..654518 - 729 WP_024319649.1 FadR/GntR family transcriptional regulator -
RlegTA1_RS27835 (RlegTA1_27835) 654822..655082 + 261 WP_027688292.1 ribbon-helix-helix domain-containing protein Antitoxin
RlegTA1_RS27840 (RlegTA1_27840) 655082..655357 + 276 WP_027688291.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RlegTA1_RS27845 (RlegTA1_27845) 655364..656371 - 1008 WP_024319652.1 LacI family DNA-binding transcriptional regulator -
RlegTA1_RS27850 (RlegTA1_27850) 656579..657901 + 1323 WP_027688290.1 alpha-L-fucosidase -
RlegTA1_RS27855 (RlegTA1_27855) 657952..659175 + 1224 WP_018072986.1 sugar ABC transporter substrate-binding protein -
RlegTA1_RS27860 (RlegTA1_27860) 659258..660232 + 975 WP_018482413.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..805037 805037


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10814.49 Da        Isoelectric Point: 10.2922

>T226627 WP_027688291.1 NZ_CP088105:655082-655357 [Rhizobium ruizarguesonis]
MGIKWTSKAASDVARLYDFLTPVDRQAAVRTVRALTAAPARLLEQPRLGERLEEFDPREVRRILVGRYELRYEIQQSMIY
VLRLWHTREDR

Download         Length: 276 bp

>T226627 NZ_CP122585:c4453-4139 [Klebsiella pneumoniae]
ATGCCACAGGTAACGATTTCCGCGCTGGCACAGCGAGATTTACAACGCCTCCAGGACTTTCTCAAAACCAAAAATCGGCT
GGCAGCCAGAAAAGCCGGTGAGGTGATCGTCCGGGCTATCCAGCAACTGAAAACATTGCCAGACATTGGCCGCCCGGTGC
CATTTCTGCCGCTGGAATATCAGGAACTGGTGATCGGGTTTGGCGACAGTGGCTATGTGATGCTCTACCGCCACGACCGG
GAAATGGACCGGATTGTGATCGTCACCGTCAGGCATCAGAAAGAATCCGGGTATCCGGGGGCAGACAGCCTCTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9756.97 Da        Isoelectric Point: 4.4964

>AT226627 WP_027688292.1 NZ_CP088105:654822-655082 [Rhizobium ruizarguesonis]
METKVLTAHVPLPLAQKVDQLASRLERSRGWIVKQALTAWIDQEEERRRLTLEALADVDDGNLVEHQSVQAWADSLDSDE
PISLPR

Download         Length: 261 bp

>AT226627 NZ_CP122585:c4719-4441 [Klebsiella pneumoniae]
ATGTCATCAGCAACATCCATCAGGCTCGATGAAGAACTTAAGGACCGGCTGAAAACGCTGGCCGATGACCGGCACCGCTC
AGCGCACGCGCTAATGCTGGAGGCAATCACCGAATACATCGACCGGGAAGAGAAGCGCAGCCAGTACCTGCGGGACGGAC
AAGCCGCATGGCAGCACTATCAGGAAACGGGTCTGCACCTTACTGCGGAAGAAGCAGAAGCCTGGATAAGTACCTGGGGA
ACTGAGAACGAGCAGGATGCTCCGCCATGCCACAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References