Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 275398..276000 Replicon chromosome
Accession NZ_CP088104
Organism Rhizobium ruizarguesonis strain TA1

Toxin (Protein)


Gene name relE Uniprot ID A0A4Q8ZZ56
Locus tag RlegTA1_RS01410 Protein ID WP_018072489.1
Coordinates 275398..275643 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4Q8ZYY9
Locus tag RlegTA1_RS01415 Protein ID WP_018072490.1
Coordinates 275653..276000 (+) Length 116 a.a.

Genomic Context

RlegTA1_RS01370RlegTA1_RS01375RlegTA1_RS01380RlegTA1_RS01385RlegTA1_RS01390RlegTA1_RS01395RlegTA1_RS01400RlegTA1_RS01410RlegTA1_RS01415RlegTA1_RS01420RlegTA1_RS01425RlegTA1_RS01430RlegTA1_RS01435
Location: 270821..271252 (432 bp)
Type: Others
Protein ID: WP_012755989.1
Location: 271369..272667 (1299 bp)
Type: Others
Protein ID: WP_027689562.1
Location: 272672..273145 (474 bp)
Type: Others
Protein ID: WP_018072486.1
Location: 273142..273627 (486 bp)
Type: Others
Protein ID: WP_017992883.1
Location: 273751..273969 (219 bp)
Type: Others
Protein ID: WP_003545338.1
Location: 274027..274647 (621 bp)
Type: Others
Protein ID: WP_003545339.1
Location: 274781..274993 (213 bp)
Type: Others
Protein ID: WP_017990235.1
Location: 275398..275643 (246 bp)
Type: Toxin
Protein ID: WP_018072489.1
Location: 275653..276000 (348 bp)
Type: Antitoxin
Protein ID: WP_018072490.1
Location: 276301..276564 (264 bp)
Type: Others
Protein ID: Protein_278
Location: 276572..278017 (1446 bp)
Type: Others
Protein ID: WP_027689563.1
Location: 278032..279747 (1716 bp)
Type: Others
Protein ID: WP_027689564.1
Location: 279838..280413 (576 bp)
Type: Others
Protein ID: WP_018072494.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
RlegTA1_RS01370 (RlegTA1_01370)270821..271252+432WP_012755989.1DUF2948 family protein-
RlegTA1_RS01375 (RlegTA1_01375)271369..272667+1299WP_027689562.1histidinol dehydrogenase-
RlegTA1_RS01380 (RlegTA1_01380)272672..273145+474WP_018072486.1UPF0262 family protein-
RlegTA1_RS01385 (RlegTA1_01385)273142..273627+486WP_017992883.1low molecular weight phosphatase family protein-
RlegTA1_RS01390 (RlegTA1_01390)273751..273969+219WP_003545338.1translation initiation factor IF-1-
RlegTA1_RS01395 (RlegTA1_01395)274027..274647+621WP_003545339.1Maf-like protein-
RlegTA1_RS01400 (RlegTA1_01400)274781..274993+213WP_017990235.1DNA gyrase inhibitor YacG-
RlegTA1_RS01410 (RlegTA1_01410)275398..275643+246WP_018072489.1cytotoxic translational repressor of toxin-antitoxin stability systemToxin
RlegTA1_RS01415 (RlegTA1_01415)275653..276000+348WP_018072490.1helix-turn-helix transcriptional regulatorAntitoxin
RlegTA1_RS01420 (RlegTA1_01420)276301..276564-264Protein_278transposase-
RlegTA1_RS01425 (RlegTA1_01425)276572..278017-1446WP_027689563.1HlyD family type I secretion periplasmic adaptor subunit-
RlegTA1_RS01430 (RlegTA1_01430)278032..279747-1716WP_027689564.1type I secretion system permease/ATPase-
RlegTA1_RS01435 (RlegTA1_01435)279838..280413-576WP_018072494.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(60-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8978.54 Da        Isoelectric Point: 10.6821

>T226624 WP_018072489.1 NZ_CP088104:275398-275643 [Rhizobium ruizarguesonis]
MKKIAYSKAAAKALRKMQPKRAAAIVAKVEAFANGETVDLKKLQGSDFFRIRVGQDRVVIDDQTMQVLVIKAGPRGDIYN
E

Download         Length: 246 bp

>T226624 NZ_CP122579:c139248-138805 [Klebsiella pneumoniae]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAACAGGCGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCATCCTGCCCTGGGACCGGGCC
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTCGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
TGGGCACGCTATCGCGGCCGGCGCCGTCCTAGTGACGAACAATGTGAGAGAGTTTGAGCGGGTGCCGGGTCTGGTGCTGG
AAGACTGGGTGAAGAAAGCCGCTCTCTGCAGGGTAATTTCTTGA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12533.12 Da        Isoelectric Point: 4.3851

>AT226624 WP_018072490.1 NZ_CP088104:275653-276000 [Rhizobium ruizarguesonis]
MGEIQKLTIDGKGYVLLSEDDYQDLVDVSDARAAKARIDAGEETWPEDVVKALIAGEDPVRVFRKHRGMSIKELAKKSGL
SQPYLSEIETGKKEGSLDALRSIASALDVDLDDVA

Download         Length: 348 bp

>AT226624 NZ_CP122579:c139475-139245 [Klebsiella pneumoniae]
ATGCGCACAGTTTCGATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGACGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
ACAGGGCCGCTCCGGACTTTATGGCGGAGCGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A4Q8ZZ56

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A4Q8ZYY9

References