Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 5737..6377 Replicon plasmid pCC829_3
Accession NZ_CP088103
Organism Bradyrhizobium japonicum strain CC829

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BjapCC829_RS49755 Protein ID WP_231146011.1
Coordinates 5737..6123 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BjapCC829_RS49760 Protein ID WP_231146012.1
Coordinates 6123..6377 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BjapCC829_RS49730 (BjapCC829_49730) 1261..2280 + 1020 WP_231146006.1 plasmid partitioning protein RepB -
BjapCC829_RS49735 (BjapCC829_49735) 2448..3755 + 1308 WP_231146007.1 plasmid replication protein RepC -
BjapCC829_RS49740 (BjapCC829_49740) 3986..4234 + 249 WP_231146008.1 type II toxin-antitoxin system VapB family antitoxin -
BjapCC829_RS49745 (BjapCC829_49745) 4231..4644 + 414 WP_231146009.1 type II toxin-antitoxin system VapC family toxin -
BjapCC829_RS49750 (BjapCC829_49750) 4664..5734 - 1071 WP_231146010.1 tyrosine-type recombinase/integrase -
BjapCC829_RS49755 (BjapCC829_49755) 5737..6123 - 387 WP_231146011.1 type II toxin-antitoxin system VapC family toxin Toxin
BjapCC829_RS49760 (BjapCC829_49760) 6123..6377 - 255 WP_231146012.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BjapCC829_RS49765 (BjapCC829_49765) 6468..6518 + 51 Protein_8 hypothetical protein -
BjapCC829_RS49770 (BjapCC829_49770) 6531..6815 + 285 WP_231146013.1 hypothetical protein -
BjapCC829_RS49775 (BjapCC829_49775) 6875..8053 + 1179 WP_231146014.1 TniQ family protein -
BjapCC829_RS49780 (BjapCC829_49780) 8150..9091 + 942 WP_231146015.1 DUF1403 family protein -
BjapCC829_RS49785 (BjapCC829_49785) 9093..9785 + 693 WP_231146016.1 SMC-Scp complex subunit ScpB -
BjapCC829_RS49790 (BjapCC829_49790) 9964..10156 - 193 Protein_13 transposase -
BjapCC829_RS49795 (BjapCC829_49795) 10210..10567 - 358 Protein_14 IS4 family transposase -
BjapCC829_RS49800 (BjapCC829_49800) 10528..10722 - 195 WP_231146017.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..109937 109937


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13847.65 Da        Isoelectric Point: 4.7313

>T226623 WP_231146011.1 NZ_CP088103:c6123-5737 [Bradyrhizobium japonicum]
MVIDTSVIVAIAFNEPEATSFRERIAEDSVRLISAATVFEATIVIETRLGEAGGAELDLWLHKADVEVVAVTAGHADQAR
RAWRRYGKGRHPAGLNFGDCFSYALAALSGEPLLFKGNDFVQTEIQAA

Download         Length: 387 bp

>T226623 NZ_CP122579:c88785-88315 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
TTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAACTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9429.64 Da        Isoelectric Point: 6.3612

>AT226623 WP_231146012.1 NZ_CP088103:c6377-6123 [Bradyrhizobium japonicum]
MALSIKDRETEQLARTLAARTGESITVATRRALEERLRRTGSQARKAALLEDLEAIQRRWNALPILDNRAPDEIVGYDEN
GIPS

Download         Length: 255 bp

>AT226623 NZ_CP122579:c89225-88782 [Klebsiella pneumoniae]
ATGAAAACATTTAGTTTGTCCTCAACTCCAGCCAGATCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGCGAATCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCGACCACGTTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAAGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAGACAGGAGCGTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References