Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 5737..6377 Replicon plasmid pCC829_3
Accession NZ_CP088103
Organism Bradyrhizobium japonicum strain CC829

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BjapCC829_RS49755 Protein ID WP_231146011.1
Coordinates 5737..6123 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BjapCC829_RS49760 Protein ID WP_231146012.1
Coordinates 6123..6377 (-) Length 85 a.a.

Genomic Context

BjapCC829_RS49730BjapCC829_RS49735BjapCC829_RS49740BjapCC829_RS49745BjapCC829_RS49765BjapCC829_RS49770BjapCC829_RS49775BjapCC829_RS49780BjapCC829_RS49785BjapCC829_RS49750BjapCC829_RS49755BjapCC829_RS49760BjapCC829_RS49790BjapCC829_RS49795BjapCC829_RS49800
Location: 1261..2280 (1020 bp)
Type: Others
Protein ID: WP_231146006.1
Location: 2448..3755 (1308 bp)
Type: Others
Protein ID: WP_231146007.1
Location: 3986..4234 (249 bp)
Type: Others
Protein ID: WP_231146008.1
Location: 4231..4644 (414 bp)
Type: Others
Protein ID: WP_231146009.1
Location: 6468..6518 (51 bp)
Type: Others
Protein ID: Protein_8
Location: 6531..6815 (285 bp)
Type: Others
Protein ID: WP_231146013.1
Location: 6875..8053 (1179 bp)
Type: Others
Protein ID: WP_231146014.1
Location: 8150..9091 (942 bp)
Type: Others
Protein ID: WP_231146015.1
Location: 9093..9785 (693 bp)
Type: Others
Protein ID: WP_231146016.1
Location: 4664..5734 (1071 bp)
Type: Others
Protein ID: WP_231146010.1
Location: 5737..6123 (387 bp)
Type: Toxin
Protein ID: WP_231146011.1
Location: 6123..6377 (255 bp)
Type: Antitoxin
Protein ID: WP_231146012.1
Location: 9964..10156 (193 bp)
Type: Others
Protein ID: Protein_13
Location: 10210..10567 (358 bp)
Type: Others
Protein ID: Protein_14
Location: 10528..10722 (195 bp)
Type: Others
Protein ID: WP_231146017.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BjapCC829_RS49730 (BjapCC829_49730)1261..2280+1020WP_231146006.1plasmid partitioning protein RepB-
BjapCC829_RS49735 (BjapCC829_49735)2448..3755+1308WP_231146007.1plasmid replication protein RepC-
BjapCC829_RS49740 (BjapCC829_49740)3986..4234+249WP_231146008.1type II toxin-antitoxin system VapB family antitoxin-
BjapCC829_RS49745 (BjapCC829_49745)4231..4644+414WP_231146009.1type II toxin-antitoxin system VapC family toxin-
BjapCC829_RS49750 (BjapCC829_49750)4664..5734-1071WP_231146010.1tyrosine-type recombinase/integrase-
BjapCC829_RS49755 (BjapCC829_49755)5737..6123-387WP_231146011.1type II toxin-antitoxin system VapC family toxinToxin
BjapCC829_RS49760 (BjapCC829_49760)6123..6377-255WP_231146012.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
BjapCC829_RS49765 (BjapCC829_49765)6468..6518+51Protein_8hypothetical protein-
BjapCC829_RS49770 (BjapCC829_49770)6531..6815+285WP_231146013.1hypothetical protein-
BjapCC829_RS49775 (BjapCC829_49775)6875..8053+1179WP_231146014.1TniQ family protein-
BjapCC829_RS49780 (BjapCC829_49780)8150..9091+942WP_231146015.1DUF1403 family protein-
BjapCC829_RS49785 (BjapCC829_49785)9093..9785+693WP_231146016.1SMC-Scp complex subunit ScpB-
BjapCC829_RS49790 (BjapCC829_49790)9964..10156-193Protein_13transposase-
BjapCC829_RS49795 (BjapCC829_49795)10210..10567-358Protein_14IS4 family transposase-
BjapCC829_RS49800 (BjapCC829_49800)10528..10722-195WP_231146017.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid--1..109937109937


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13847.65 Da        Isoelectric Point: 4.7313

>T226623 WP_231146011.1 NZ_CP088103:c6123-5737 [Bradyrhizobium japonicum]
MVIDTSVIVAIAFNEPEATSFRERIAEDSVRLISAATVFEATIVIETRLGEAGGAELDLWLHKADVEVVAVTAGHADQAR
RAWRRYGKGRHPAGLNFGDCFSYALAALSGEPLLFKGNDFVQTEIQAA

Download         Length: 387 bp

>T226623 NZ_CP122579:c88785-88315 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
TTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAACTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9429.64 Da        Isoelectric Point: 6.3612

>AT226623 WP_231146012.1 NZ_CP088103:c6377-6123 [Bradyrhizobium japonicum]
MALSIKDRETEQLARTLAARTGESITVATRRALEERLRRTGSQARKAALLEDLEAIQRRWNALPILDNRAPDEIVGYDEN
GIPS

Download         Length: 255 bp

>AT226623 NZ_CP122579:c89225-88782 [Klebsiella pneumoniae]
ATGAAAACATTTAGTTTGTCCTCAACTCCAGCCAGATCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGCGAATCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCGACCACGTTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAAGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAGACAGGAGCGTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References