Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 166093..166666 Replicon chromosome
Accession NZ_CP088095
Organism Rhizobium leguminosarum bv. viciae strain SU303

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag RlegSU303_RS00840 Protein ID WP_231283834.1
Coordinates 166418..166666 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag RlegSU303_RS00835 Protein ID WP_131718628.1
Coordinates 166093..166416 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RlegSU303_RS00810 (RlegSU303_00810) 161500..161700 - 201 WP_038613687.1 hypothetical protein -
RlegSU303_RS00815 (RlegSU303_00815) 161938..162870 + 933 WP_231283366.1 methyltransferase domain-containing protein -
RlegSU303_RS00820 (RlegSU303_00820) 163055..163630 - 576 WP_131644328.1 AAA family ATPase -
RlegSU303_RS00825 (RlegSU303_00825) 163705..165195 - 1491 WP_131718626.1 MDR family MFS transporter -
RlegSU303_RS00830 (RlegSU303_00830) 165455..165865 - 411 WP_131718627.1 hypothetical protein -
RlegSU303_RS00835 (RlegSU303_00835) 166093..166416 - 324 WP_131718628.1 putative addiction module antidote protein Antitoxin
RlegSU303_RS00840 (RlegSU303_00840) 166418..166666 - 249 WP_231283834.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RlegSU303_RS00850 (RlegSU303_00850) 167584..168543 - 960 WP_131718630.1 nitronate monooxygenase family protein -
RlegSU303_RS00855 (RlegSU303_00855) 168828..170027 + 1200 WP_131718631.1 regulator -
RlegSU303_RS00860 (RlegSU303_00860) 170077..170958 - 882 WP_017958843.1 polyphosphate kinase 2 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-81)

Antitoxin

Uncharacterized protein HI1420

(14-95)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9300.75 Da        Isoelectric Point: 9.9571

>T226614 WP_231283834.1 NZ_CP088095:c166666-166418 [Rhizobium leguminosarum bv. viciae]
MRKLKDRNARDRIVTRIVRAEAGNLGDHKFFDGIGELRLDYGPGYRLYFAMQGSVVVILLCGGDKGSQDRDIKRAIEMSK
EI

Download         Length: 249 bp

>T226614 NZ_CP122578:798724-799134 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11396.68 Da        Isoelectric Point: 4.4585

>AT226614 WP_131718628.1 NZ_CP088095:c166416-166093 [Rhizobium leguminosarum bv. viciae]
MALEIIPFDATEFLDTEESQAHLIEDAFESGDAGYIAHALGVVAKARGMSQVARDAGVTREALYKSLSEKGDPKLSTLIG
VAAALGYKLTATRVDDSDTHEDARRSA

Download         Length: 324 bp

>AT226614 NZ_CP122578:798477-798743 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References