Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 118991..119763 Replicon plasmid pWSM1455_2
Accession NZ_CP088092
Organism Rhizobium laguerreae strain WSM1455

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag RlegWSM1455_RS29710 Protein ID WP_131640724.1
Coordinates 119275..119763 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag RlegWSM1455_RS29705 Protein ID WP_077980259.1
Coordinates 118991..119275 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RlegWSM1455_RS29685 (RlegWSM1455_29685) 114779..116101 + 1323 WP_077979885.1 aspartate aminotransferase family protein -
RlegWSM1455_RS29690 (RlegWSM1455_29690) 116576..117382 - 807 WP_077979884.1 sugar phosphate isomerase/epimerase -
RlegWSM1455_RS29695 (RlegWSM1455_29695) 117447..117623 + 177 WP_231285782.1 hypothetical protein -
RlegWSM1455_RS29700 (RlegWSM1455_29700) 117772..118520 + 749 Protein_104 sulfite exporter TauE/SafE family protein -
RlegWSM1455_RS29705 (RlegWSM1455_29705) 118991..119275 + 285 WP_077980259.1 DUF1778 domain-containing protein Antitoxin
RlegWSM1455_RS29710 (RlegWSM1455_29710) 119275..119763 + 489 WP_131640724.1 GNAT family N-acetyltransferase Toxin
RlegWSM1455_RS29715 (RlegWSM1455_29715) 120033..120305 - 273 WP_206118595.1 helix-turn-helix transcriptional regulator -
RlegWSM1455_RS29720 (RlegWSM1455_29720) 120691..120903 - 213 WP_167383840.1 hypothetical protein -
RlegWSM1455_RS29725 (RlegWSM1455_29725) 121499..121762 + 264 WP_064655279.1 DUF982 domain-containing protein -
RlegWSM1455_RS29730 (RlegWSM1455_29730) 122054..122254 - 201 WP_077980283.1 hypothetical protein -
RlegWSM1455_RS29735 (RlegWSM1455_29735) 122278..122592 - 315 WP_077980256.1 hypothetical protein -
RlegWSM1455_RS29740 (RlegWSM1455_29740) 122673..122873 - 201 WP_003548617.1 hypothetical protein -
RlegWSM1455_RS29745 (RlegWSM1455_29745) 123006..123167 + 162 Protein_113 ATP-dependent DNA ligase -
RlegWSM1455_RS29750 (RlegWSM1455_29750) 123219..123509 - 291 WP_077980255.1 CopG family transcriptional regulator -
RlegWSM1455_RS29755 (RlegWSM1455_29755) 123655..123927 - 273 WP_077980254.1 hypothetical protein -
RlegWSM1455_RS29760 (RlegWSM1455_29760) 123927..124352 - 426 WP_042941739.1 hypothetical protein -
RlegWSM1455_RS29765 (RlegWSM1455_29765) 124558..124737 - 180 WP_231285783.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..521923 521923


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(1-93)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17339.91 Da        Isoelectric Point: 7.9271

>T226612 WP_131640724.1 NZ_CP088092:119275-119763 [Rhizobium laguerreae]
MLSAPTLLGEAHDLQLFDSGHDSLDEWLRRRARANQVSGASRTYVVCEGERVVGYYCLSSGALAVADSPGAIRRNMPDPV
PMAVLGRLAIDRNWQGKGIGAALLQDAVLRTGQAAHIMGIRGLLVHAISDEAKAFYEHFGFTSSPANPMALVLSLKAQVG
LK

Download         Length: 489 bp

>T226612 NZ_CP122578:327908-328276 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACTGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10776.15 Da        Isoelectric Point: 9.7293

>AT226612 WP_077980259.1 NZ_CP088092:118991-119275 [Rhizobium laguerreae]
MTSKNATDTHTRAVNLRVREDVRVLIDRAAKAHGKTRSDFMIDASRRAAEDALLDQTLVRVDPDSYKHYLAVLDQPPNSE
GFERLMNTRKPWQP

Download         Length: 285 bp

>AT226612 NZ_CP122578:327690-327911 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References