Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 721610..722277 Replicon plasmid pWSM1455_1
Accession NZ_CP088091
Organism Rhizobium laguerreae strain WSM1455

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RlegWSM1455_RS27620 Protein ID WP_131661888.1
Coordinates 721610..722053 (-) Length 148 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RlegWSM1455_RS27625 Protein ID WP_131642915.1
Coordinates 722050..722277 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RlegWSM1455_RS27580 (RlegWSM1455_27580) 716965..717459 + 495 WP_231285538.1 lipocalin-like domain-containing protein -
RlegWSM1455_RS27585 (RlegWSM1455_27585) 717791..718126 + 336 WP_231285539.1 hypothetical protein -
RlegWSM1455_RS27590 (RlegWSM1455_27590) 718111..718437 + 327 WP_231285540.1 hypothetical protein -
RlegWSM1455_RS27595 (RlegWSM1455_27595) 718729..718968 - 240 Protein_737 SOS response-associated peptidase -
RlegWSM1455_RS27600 (RlegWSM1455_27600) 718977..719132 + 156 Protein_738 transposase -
RlegWSM1455_RS27605 (RlegWSM1455_27605) 719236..719427 + 192 WP_206108860.1 hypothetical protein -
RlegWSM1455_RS27610 (RlegWSM1455_27610) 719444..720775 - 1332 WP_131662553.1 epoxide hydrolase -
RlegWSM1455_RS27615 (RlegWSM1455_27615) 721244..721363 - 120 Protein_741 SDR family NAD(P)-dependent oxidoreductase -
RlegWSM1455_RS27620 (RlegWSM1455_27620) 721610..722053 - 444 WP_131661888.1 PIN domain-containing protein Toxin
RlegWSM1455_RS27625 (RlegWSM1455_27625) 722050..722277 - 228 WP_131642915.1 CopG family transcriptional regulator Antitoxin
RlegWSM1455_RS34310 722295..722420 - 126 WP_260685381.1 hypothetical protein -
RlegWSM1455_RS27630 (RlegWSM1455_27630) 722411..723129 + 719 Protein_745 hypothetical protein -
RlegWSM1455_RS27635 (RlegWSM1455_27635) 723223..723987 + 765 WP_077976746.1 metallophosphoesterase -
RlegWSM1455_RS27640 (RlegWSM1455_27640) 724181..724477 + 297 WP_077976747.1 DUF1778 domain-containing protein -
RlegWSM1455_RS27645 (RlegWSM1455_27645) 724474..724971 + 498 WP_077976748.1 GNAT family N-acetyltransferase -
RlegWSM1455_RS27650 (RlegWSM1455_27650) 725419..726477 + 1059 WP_231283901.1 GSU2403 family nucleotidyltransferase fold protein -
RlegWSM1455_RS34315 726620..726895 - 276 Protein_750 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..1064136 1064136


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 148 a.a.        Molecular weight: 15537.79 Da        Isoelectric Point: 8.1078

>T226609 WP_131661888.1 NZ_CP088091:c722053-721610 [Rhizobium laguerreae]
VTFLLDVNVLIALIDPGHVAHDDAHAWFAAIGQSAWATCPITENGVIRIVGNPKYPNSPGSPSLVMEIVRKLRSLPGHSF
WPDDVSLVGSGDIAPTKILTSGQVTDTYLLALAKARGGQLATFDRKLSAAAVTRGNSALHLITTSRS

Download         Length: 444 bp

>T226609 NZ_CP122574:c103853-103383 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
TTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAACTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8232.44 Da        Isoelectric Point: 7.0120

>AT226609 WP_131642915.1 NZ_CP088091:c722277-722050 [Rhizobium laguerreae]
MRTTLAIDDDVLIAAKAMATQQHRSVGEVISELARRSLRRPPSSGERNGIPLLSTRPDTPPVTLEIVNAMRDELP

Download         Length: 228 bp

>AT226609 NZ_CP122574:c104293-103850 [Klebsiella pneumoniae]
ATGAAAACATTTAGTTTGTCCTCAACTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGCGAATCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCGACCACGTTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAAGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAGACAGGAGCGTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References