Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 4198006..4198643 Replicon chromosome
Accession NZ_CP088089
Organism Bradyrhizobium canariense strain WU425

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BcanWU425_RS20390 Protein ID WP_231188457.1
Coordinates 4198248..4198643 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BcanWU425_RS20385 Protein ID WP_085353162.1
Coordinates 4198006..4198248 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BcanWU425_RS20355 (BcanWU425_20355) 4194233..4194490 - 258 WP_018457991.1 hypothetical protein -
BcanWU425_RS20360 (BcanWU425_20360) 4194738..4195232 + 495 WP_204511274.1 pantetheine-phosphate adenylyltransferase -
BcanWU425_RS20365 (BcanWU425_20365) 4195274..4195837 + 564 WP_231188456.1 peptidylprolyl isomerase -
BcanWU425_RS20370 (BcanWU425_20370) 4195846..4196271 + 426 WP_018457988.1 hypothetical protein -
BcanWU425_RS20375 (BcanWU425_20375) 4196268..4196732 + 465 WP_018457987.1 peptidylprolyl isomerase -
BcanWU425_RS20380 (BcanWU425_20380) 4196875..4197948 + 1074 WP_204511272.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
BcanWU425_RS20385 (BcanWU425_20385) 4198006..4198248 + 243 WP_085353162.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BcanWU425_RS20390 (BcanWU425_20390) 4198248..4198643 + 396 WP_231188457.1 type II toxin-antitoxin system VapC family toxin Toxin
BcanWU425_RS20395 (BcanWU425_20395) 4198757..4199794 - 1038 WP_231188458.1 aspartate-semialdehyde dehydrogenase -
BcanWU425_RS20400 (BcanWU425_20400) 4200014..4200616 - 603 WP_204511270.1 PepSY domain-containing protein -
BcanWU425_RS20405 (BcanWU425_20405) 4200864..4201610 - 747 WP_018457980.1 TetR/AcrR family transcriptional regulator -
BcanWU425_RS20410 (BcanWU425_20410) 4201744..4202928 - 1185 WP_204511269.1 patatin-like phospholipase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(2-79)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 13827.01 Da        Isoelectric Point: 5.0898

>T226602 WP_231188457.1 NZ_CP088089:4198248-4198643 [Bradyrhizobium canariense]
MVLDTSAIVATVTNEPDGQRYRKAMLDAASLSMSAVAILETKIVLSARFGASAVKFFDELLETAGIVVVPFDADMAKGAF
EAFQRFGTGGGHPAQLNIVDCAVYALAKARSQPLLFKGADFAKTDILPALT

Download         Length: 396 bp

>T226602 NZ_CP122573:c2720562-2719240 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCTGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8872.03 Da        Isoelectric Point: 4.8146

>AT226602 WP_085353162.1 NZ_CP088089:4198006-4198248 [Bradyrhizobium canariense]
MNIRSAKVDELAQRLARLTGEDIETALERAIEERLSRVASPAVDRRAALTSFFERTAGLPVLDSRPADEILGYDRFGLPS

Download         Length: 243 bp

>AT226602 NZ_CP122573:c2720828-2720562 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References