Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 1103113..1104725 | Replicon | chromosome |
| Accession | NZ_CP088088 | ||
| Organism | Bradyrhizobium diazoefficiens strain CB1809 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A837C678 |
| Locus tag | BdzoCB1809_RS05175 | Protein ID | WP_049832575.1 |
| Coordinates | 1103802..1104725 (+) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | - |
| Locus tag | BdzoCB1809_RS05170 | Protein ID | WP_231166619.1 |
| Coordinates | 1103113..1103805 (+) | Length | 231 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BdzoCB1809_RS05160 (BdzoCB1809_05160) | 1098197..1098754 | - | 558 | WP_074077613.1 | hypothetical protein | - |
| BdzoCB1809_RS05165 (BdzoCB1809_05165) | 1098881..1102939 | - | 4059 | WP_028175467.1 | helix-turn-helix transcriptional regulator | - |
| BdzoCB1809_RS05170 (BdzoCB1809_05170) | 1103113..1103805 | + | 693 | WP_231166619.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| BdzoCB1809_RS05175 (BdzoCB1809_05175) | 1103802..1104725 | + | 924 | WP_049832575.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| BdzoCB1809_RS05180 (BdzoCB1809_05180) | 1104880..1105962 | - | 1083 | WP_049832576.1 | AAA family ATPase | - |
| BdzoCB1809_RS05185 (BdzoCB1809_05185) | 1105965..1106891 | - | 927 | WP_157862142.1 | toprim domain-containing protein | - |
| BdzoCB1809_RS05190 (BdzoCB1809_05190) | 1106923..1107129 | - | 207 | WP_028175471.1 | helix-turn-helix domain-containing protein | - |
| BdzoCB1809_RS05195 (BdzoCB1809_05195) | 1107206..1107919 | - | 714 | WP_131234232.1 | hypothetical protein | - |
| BdzoCB1809_RS05200 (BdzoCB1809_05200) | 1107935..1108453 | - | 519 | WP_131234233.1 | hypothetical protein | - |
| BdzoCB1809_RS05205 (BdzoCB1809_05205) | 1108488..1109657 | - | 1170 | WP_039187218.1 | tyrosine-type recombinase/integrase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1092159..1108453 | 16294 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 34339.39 Da Isoelectric Point: 4.9777
>T226599 WP_049832575.1 NZ_CP088088:1103802-1104725 [Bradyrhizobium diazoefficiens]
MIGKPLKDPGASIRQRLLNHAKEHGDEYQRILTRYAIERLLFRLSQTEARERYVLKGAMLFVTWPEQVFRPTGDLDLLGQ
GDPDPAAIIDLFTLICQVEAPADGIIFDPSTLQVEAVREEEKYQGVRLSLRGRLGTAVIPVQVDIGFGDSVHPAPSRNNF
PSLLPDLPAADVLMYPPETVIAEKFEAMIRFGEANGRIKDFHDIWVTARTFAFNLSTLVEAVSGTLQRRETAFPTEMPVA
LTSQFAEMADKQALWTGFLRRNPPTLPPPPLGDLLAELRRFFEPVLAALPLPESATGRWNPDRGAWE
MIGKPLKDPGASIRQRLLNHAKEHGDEYQRILTRYAIERLLFRLSQTEARERYVLKGAMLFVTWPEQVFRPTGDLDLLGQ
GDPDPAAIIDLFTLICQVEAPADGIIFDPSTLQVEAVREEEKYQGVRLSLRGRLGTAVIPVQVDIGFGDSVHPAPSRNNF
PSLLPDLPAADVLMYPPETVIAEKFEAMIRFGEANGRIKDFHDIWVTARTFAFNLSTLVEAVSGTLQRRETAFPTEMPVA
LTSQFAEMADKQALWTGFLRRNPPTLPPPPLGDLLAELRRFFEPVLAALPLPESATGRWNPDRGAWE
Download Length: 924 bp
>T226599 NZ_CP122573:737508-737993 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA
Antitoxin
Download Length: 231 a.a. Molecular weight: 25491.54 Da Isoelectric Point: 10.3648
>AT226599 WP_231166619.1 NZ_CP088088:1103113-1103805 [Bradyrhizobium diazoefficiens]
MTSAANLQMLFNVDKSADVPTKDNKMTQRHVLPYRERALNLVRARGIARARDFKAAGIPLVYLKRLTDTGELVRLGRGLY
QDPDRVGEDVAHNLAEAARAVPNGVVSLASALRYHGLTTQLPHAVWLTIPHKARTPKAIGFPLEIVRATGDVMTAGVEHV
QVEGVDVPIYGVAKTIADCFKHRRHIGEDVAIEALRDALRLRKTTVSDVMRYAEIDRVAERIRPVLKALQ
MTSAANLQMLFNVDKSADVPTKDNKMTQRHVLPYRERALNLVRARGIARARDFKAAGIPLVYLKRLTDTGELVRLGRGLY
QDPDRVGEDVAHNLAEAARAVPNGVVSLASALRYHGLTTQLPHAVWLTIPHKARTPKAIGFPLEIVRATGDVMTAGVEHV
QVEGVDVPIYGVAKTIADCFKHRRHIGEDVAIEALRDALRLRKTTVSDVMRYAEIDRVAERIRPVLKALQ
Download Length: 693 bp
>AT226599 NZ_CP122573:737218-737511 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|