Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 5150869..5152553 Replicon chromosome
Accession NZ_CP088080
Organism Agarivorans sp. B2Z047

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag LQZ07_RS23880 Protein ID WP_249483420.1
Coordinates 5151333..5152553 (+) Length 407 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag LQZ07_RS23875 Protein ID WP_152785258.1
Coordinates 5150869..5151336 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQZ07_RS23845 (LQZ07_23845) 5145943..5146344 + 402 WP_152785270.1 hypothetical protein -
LQZ07_RS23850 (LQZ07_23850) 5146594..5146785 + 192 WP_152785268.1 hypothetical protein -
LQZ07_RS23855 (LQZ07_23855) 5146792..5147409 + 618 WP_152785266.1 tyrosine-type recombinase/integrase -
LQZ07_RS23860 (LQZ07_23860) 5147518..5148186 + 669 WP_152785264.1 hypothetical protein -
LQZ07_RS23865 (LQZ07_23865) 5148290..5148718 + 429 WP_152785262.1 hypothetical protein -
LQZ07_RS23870 (LQZ07_23870) 5149801..5150700 + 900 WP_152785260.1 S49 family peptidase -
LQZ07_RS23875 (LQZ07_23875) 5150869..5151336 + 468 WP_152785258.1 DUF4065 domain-containing protein Antitoxin
LQZ07_RS23880 (LQZ07_23880) 5151333..5152553 + 1221 WP_249483420.1 RelA/SpoT domain-containing protein Toxin
LQZ07_RS23885 (LQZ07_23885) 5152860..5154059 + 1200 WP_249483424.1 site-specific integrase -
LQZ07_RS23890 (LQZ07_23890) 5154063..5154935 - 873 WP_152785256.1 hypothetical protein -
LQZ07_RS23895 (LQZ07_23895) 5155110..5155298 + 189 WP_152785254.1 AlpA family phage regulatory protein -
LQZ07_RS23900 (LQZ07_23900) 5155310..5155672 + 363 WP_152785252.1 hypothetical protein -
LQZ07_RS23905 (LQZ07_23905) 5155824..5156126 + 303 WP_152785250.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5145672..5164223 18551


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(86-228)

Antitoxin

Antitoxin SocA-like, Panacea domain

(32-123)


Sequences

Toxin        


Download         Length: 407 a.a.        Molecular weight: 46088.37 Da        Isoelectric Point: 7.4361

>T226591 WP_249483420.1 NZ_CP088080:5151333-5152553 [Agarivorans sp. B2Z047]
VSREHKSVVSFEIDDTPSAIESSKDFLEDYPFNFQEFLAKASDESTAKDFSYSNNSVKKAGRRLRKKEGDLKSATSTIQT
FRAAHEKPLNTIAYLIGRCCREIGVSVTPVKRLKRLETIVNKLQRKSLDGITDNQTCVTNMNDIGGCRAIFPDISSLRKV
REKLTATIENEAKTKIKIKNVHDYIAEPKPNDCGYRSVHIIYRYEHSSGKAFNIEAQLRTKMQHIWATTVEIIDILERTN
IKTHSHSPDNEKTSKQVKWEELLSIMSQYIASEERAVTLSPEELIYFASRLQDLNNDINALSRLRSFNMMSESVPNLDSK
TTRHVLLVINESKLETMVIQELENHNQAISIYNEIENAISNVEGLNTLLVSTKNMAQLADAYPNYVGDCLSFIKLLEKAM
QQPASC

Download         Length: 1221 bp

>T226591 NZ_CP122567:47286-47768 [Klebsiella pneumoniae]
GTGGGACGTATAACCGCGCCCGAGCCGTTATCCAGCGCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCACTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGAAGGGTACGA
AGAAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCTACAGGCAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGTGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGCGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17486.12 Da        Isoelectric Point: 8.6787

>AT226591 WP_152785258.1 NZ_CP088080:5150869-5151336 [Agarivorans sp. B2Z047]
MKAYHTYSAVDVALSLLKHATKQGKCFTNLQLQKLTYVCHGLSLAHFQRPLITDDVFAWKFGPVVPSVYFRFKCYGAKPI
TERLDISLDPESESILEDVVAKLGHLTGPQLVELTHREGSPWKKVWDGTHQKIIPDNLIQGHYTQIKNSGHTSSL

Download         Length: 468 bp

>AT226591 NZ_CP122567:47032-47298 [Klebsiella pneumoniae]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGTACTCATCGATGCCGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGATTCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References