Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 847759..848419 | Replicon | chromosome |
Accession | NZ_CP088019 | ||
Organism | Pectobacterium carotovorum strain 25.1 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A419ATT9 |
Locus tag | LQF52_RS03845 | Protein ID | WP_029368427.1 |
Coordinates | 848006..848419 (+) | Length | 138 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A1D7Z1Z6 |
Locus tag | LQF52_RS03840 | Protein ID | WP_005971623.1 |
Coordinates | 847759..848025 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LQF52_RS03820 (LQF52_03820) | 843737..844741 | - | 1005 | WP_039543409.1 | LacI family DNA-binding transcriptional regulator | - |
LQF52_RS03825 (LQF52_03825) | 844796..845404 | - | 609 | WP_014914174.1 | HD domain-containing protein | - |
LQF52_RS03830 (LQF52_03830) | 845683..846330 | + | 648 | WP_039543413.1 | hemolysin III family protein | - |
LQF52_RS03835 (LQF52_03835) | 846522..847523 | - | 1002 | WP_039534570.1 | tRNA-modifying protein YgfZ | - |
LQF52_RS03840 (LQF52_03840) | 847759..848025 | + | 267 | WP_005971623.1 | FAD assembly factor SdhE | Antitoxin |
LQF52_RS03845 (LQF52_03845) | 848006..848419 | + | 414 | WP_029368427.1 | protein YgfX | Toxin |
LQF52_RS03850 (LQF52_03850) | 848488..849423 | + | 936 | WP_039534572.1 | 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF | - |
LQF52_RS03855 (LQF52_03855) | 849506..849829 | - | 324 | WP_039534575.1 | hypothetical protein | - |
LQF52_RS03860 (LQF52_03860) | 849858..850376 | - | 519 | WP_039534579.1 | flavodoxin FldB | - |
LQF52_RS03865 (LQF52_03865) | 850716..851102 | - | 387 | WP_039534581.1 | thioesterase family protein | - |
LQF52_RS03870 (LQF52_03870) | 851310..852638 | - | 1329 | WP_010301826.1 | MFS transporter | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 16296.29 Da Isoelectric Point: 10.7911
>T226580 WP_029368427.1 NZ_CP088019:848006-848419 [Pectobacterium carotovorum]
VALWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR
VALWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR
Download Length: 414 bp
>T226580 NZ_CP088019:848006-848419 [Pectobacterium carotovorum]
GTGGCCCTGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGCCTATTAGTATT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTACGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAACGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTATTACTGTCATTACAAGCGGTTAACGGTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGCGATGATGAATGGCGTCACTTGCGTCAAATTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG
GTGGCCCTGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTTGTGCATGGCCTATTAGTATT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTACGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAACGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTATTACTGTCATTACAAGCGGTTAACGGTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGCGATGATGAATGGCGTCACTTGCGTCAAATTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG
Antitoxin
Download Length: 89 a.a. Molecular weight: 10507.94 Da Isoelectric Point: 5.1392
>AT226580 WP_005971623.1 NZ_CP088019:847759-848025 [Pectobacterium carotovorum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT226580 NZ_CP088019:847759-848025 [Pectobacterium carotovorum]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGCACGTTTGTACGCTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCTGTGGCGATGTGA
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGCACGTTTGTACGCTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCTGTGGCGATGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A419ATT9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1D7Z1Z6 |