Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 584171..585869 Replicon chromosome
Accession NZ_CP088019
Organism Pectobacterium carotovorum strain 25.1

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag LQF52_RS02555 Protein ID WP_231051834.1
Coordinates 584171..585100 (-) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag LQF52_RS02560 Protein ID WP_039522494.1
Coordinates 585087..585869 (-) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQF52_RS02535 (LQF52_02535) 580063..582144 - 2082 WP_231051833.1 DUF4034 domain-containing protein -
LQF52_RS02540 (LQF52_02540) 582301..582438 + 138 Protein_492 hypothetical protein -
LQF52_RS02545 (LQF52_02545) 582590..582853 - 264 WP_039543254.1 DUF2798 domain-containing protein -
LQF52_RS02550 (LQF52_02550) 582982..583884 + 903 WP_039543255.1 LysR family transcriptional regulator -
LQF52_RS02555 (LQF52_02555) 584171..585100 - 930 WP_231051834.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LQF52_RS02560 (LQF52_02560) 585087..585869 - 783 WP_039522494.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LQF52_RS02565 (LQF52_02565) 586195..586380 + 186 WP_146044070.1 ash family protein -
LQF52_RS02570 (LQF52_02570) 586331..586792 + 462 WP_119881253.1 hypothetical protein -
LQF52_RS02575 (LQF52_02575) 586789..586998 + 210 WP_039491410.1 helix-turn-helix transcriptional regulator -
LQF52_RS02580 (LQF52_02580) 587359..588246 + 888 WP_231051835.1 ParA family protein -
LQF52_RS02585 (LQF52_02585) 588243..588632 + 390 WP_231051836.1 hypothetical protein -
LQF52_RS02590 (LQF52_02590) 588625..589980 + 1356 WP_231051837.1 SPI-7-type island replicative DNA helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-262)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(2-92)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35298.71 Da        Isoelectric Point: 6.4959

>T226579 WP_231051834.1 NZ_CP088019:c585100-584171 [Pectobacterium carotovorum]
MDQRDIYARQVRLLMTALPYVAKESCFALKGGTAINLFMQDFPRLSVDIDLVYQTFMDRDTDLAAIDDALMRITESLKSQ
PRITAIRQDNKADEKRIIVNTANAQIKIEVSPVWRGLLLPPAEIPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPIAELLAPNWDIARIATLYQQEFSGMTQHETSLESLLSVTTLLPQAL
RSHFTTQDKQFLLSYKQNTPDWSLYRYPDIQHLTAIRWKQHNLSALYAKNPAKFSAAVSKLEKVLEQRF

Download         Length: 930 bp

>T226579 NZ_CP122520:22740-23021 [Escherichia coli]
ATGACCTATGAACTGGCTTTTGACCGTAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGTCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATACCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29345.67 Da        Isoelectric Point: 9.0909

>AT226579 WP_039522494.1 NZ_CP088019:c585869-585087 [Pectobacterium carotovorum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPIWVAGLT
SIALQGYSHYTELGKPQVWLTIPAYITLPGWFAAFEKSATFVVLYTSGLSVDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLSASRSVKTNRVMLYLAQRNGHPYFQYLDKSGIEVGAGKRQIVPGGWLEP
DYQITVPREFKSKGIEDGSA

Download         Length: 783 bp

>AT226579 NZ_CP122520:22499-22750 [Escherichia coli]
ATGAGCTATCAAATTCTGACAACCACAGCGGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACCGTAGCTGAAGG
TGAAGGGGACGCTGTTGCGATCCTGAACCGAAACGAACCGGCGTTCTATTGCGTTCCACCAAAACTTTACGCCTACTATC
GGGAACTCGCTGAAGATGCTGAGTTAAACGCTGTTGCTGATGAGCGCATGAAAAACCCGGAAATTGTGAAGGTTAACCTG
GATGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References