226575

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 377605..378136 Replicon chromosome
Accession NZ_CP088019
Organism Pectobacterium carotovorum strain 25.1

Toxin (Protein)


Gene name stbE Uniprot ID A0A086EVU3
Locus tag LQF52_RS01685 Protein ID WP_039282785.1
Coordinates 377849..378136 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A1V2R9J2
Locus tag LQF52_RS01680 Protein ID WP_039282788.1
Coordinates 377605..377859 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQF52_RS01655 (LQF52_01655) 373062..373652 - 591 WP_011091952.1 DnaA initiator-associating protein DiaA -
LQF52_RS01660 (LQF52_01660) 373716..374072 - 357 WP_180782501.1 YraN family protein -
LQF52_RS01665 (LQF52_01665) 374069..376087 - 2019 WP_180782488.1 penicillin-binding protein activator -
LQF52_RS01670 (LQF52_01670) 376149..377036 + 888 WP_039470360.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
LQF52_RS01680 (LQF52_01680) 377605..377859 + 255 WP_039282788.1 plasmid stabilization protein Antitoxin
LQF52_RS01685 (LQF52_01685) 377849..378136 + 288 WP_039282785.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LQF52_RS01690 (LQF52_01690) 378312..379105 + 794 Protein_324 4,5-DOPA dioxygenase extradiol -
LQF52_RS01695 (LQF52_01695) 379386..380546 - 1161 WP_010297418.1 glutathionylspermidine synthase family protein -
LQF52_RS01700 (LQF52_01700) 380557..381231 - 675 WP_010297420.1 DUF1190 family protein -
LQF52_RS01705 (LQF52_01705) 381502..382896 - 1395 WP_010297423.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11011.96 Da        Isoelectric Point: 10.7694

>T226575 WP_039282785.1 NZ_CP088019:377849-378136 [Pectobacterium carotovorum]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T226575 NZ_CP122517:c4261484-4261311 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9208.38 Da        Isoelectric Point: 3.7947

>AT226575 WP_039282788.1 NZ_CP088019:377605-377859 [Pectobacterium carotovorum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT226575 NZ_CP122517:c4261808-4261512 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CTTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086EVU3

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9J2

References