Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2430057..2430595 Replicon chromosome
Accession NZ_CP088018
Organism Ruania suaedae strain LR1S40

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LQF12_RS11185 Protein ID WP_231053014.1
Coordinates 2430057..2430323 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LQF12_RS11190 Protein ID WP_231053015.1
Coordinates 2430320..2430595 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQF12_RS11170 (LQF12_11170) 2426218..2427162 + 945 WP_231053011.1 sugar ABC transporter permease -
LQF12_RS11175 (LQF12_11175) 2427159..2428034 + 876 WP_231053012.1 carbohydrate ABC transporter permease -
LQF12_RS11180 (LQF12_11180) 2428031..2430100 + 2070 WP_231053013.1 alpha-galactosidase -
LQF12_RS11185 (LQF12_11185) 2430057..2430323 - 267 WP_231053014.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LQF12_RS11190 (LQF12_11190) 2430320..2430595 - 276 WP_231053015.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LQF12_RS11195 (LQF12_11195) 2430663..2431514 - 852 WP_231053016.1 biotin-dependent carboxyltransferase family protein -
LQF12_RS11200 (LQF12_11200) 2431514..2432110 - 597 WP_231053017.1 allophanate hydrolase subunit 1 -
LQF12_RS11205 (LQF12_11205) 2432107..2432844 - 738 WP_231053018.1 5-oxoprolinase subunit PxpA -
LQF12_RS11210 (LQF12_11210) 2432841..2433740 - 900 WP_231053019.1 hypothetical protein -
LQF12_RS11215 (LQF12_11215) 2433772..2434563 - 792 WP_231053020.1 ECF transporter S component -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 9853.40 Da        Isoelectric Point: 10.5683

>T226571 WP_231053014.1 NZ_CP088018:c2430323-2430057 [Ruania suaedae]
MTWEVQFAPSAVRGLDRLPPRIVGAVVEFITVTLPANPERMSKALSGELEGFRSARRGDYRVIFSLDAATSELLVIRVAH
RADVYRPR

Download         Length: 267 bp

>T226571 NZ_CP122517:3487421-3487639 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10299.54 Da        Isoelectric Point: 4.7238

>AT226571 WP_231053015.1 NZ_CP088018:c2430595-2430320 [Ruania suaedae]
MKTVTLSEAKDKLSAYLDEVETEHEIVRITRHGRGAAVLISQDDLDSLRETIFWLSQPGIREDIAEAQRSVEEKSTMSAD
DVRARYGLPPR

Download         Length: 276 bp

>AT226571 NZ_CP122517:3487021-3487395 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCTTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References