Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1135462..1136120 Replicon chromosome
Accession NZ_CP088014
Organism Bradyrhizobium daqingense strain CCBAU 15774

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LPJ38_RS05265 Protein ID WP_145630235.1
Coordinates 1135462..1135866 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LPJ38_RS05270 Protein ID WP_145630234.1
Coordinates 1135866..1136120 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPJ38_RS05245 (LPJ38_05245) 1130768..1133338 - 2571 WP_145630239.1 FtsX-like permease family protein -
LPJ38_RS05250 (LPJ38_05250) 1133335..1134057 - 723 WP_145630238.1 ABC transporter ATP-binding protein -
LPJ38_RS05255 (LPJ38_05255) 1134113..1134748 + 636 WP_167520326.1 arylesterase -
LPJ38_RS05260 (LPJ38_05260) 1134921..1135457 + 537 WP_145630236.1 RNA 2',3'-cyclic phosphodiesterase -
LPJ38_RS05265 (LPJ38_05265) 1135462..1135866 - 405 WP_145630235.1 type II toxin-antitoxin system VapC family toxin Toxin
LPJ38_RS05270 (LPJ38_05270) 1135866..1136120 - 255 WP_145630234.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LPJ38_RS05275 (LPJ38_05275) 1136314..1137498 + 1185 WP_145630233.1 cell division protein ZapE -
LPJ38_RS05280 (LPJ38_05280) 1137730..1138698 + 969 WP_025032846.1 malate dehydrogenase -
LPJ38_RS05285 (LPJ38_05285) 1138907..1140103 + 1197 WP_145630232.1 ADP-forming succinate--CoA ligase subunit beta -
LPJ38_RS05290 (LPJ38_05290) 1140108..1140587 + 480 WP_145630231.1 DUF1579 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14392.27 Da        Isoelectric Point: 4.7434

>T226568 WP_145630235.1 NZ_CP088014:c1135866-1135462 [Bradyrhizobium daqingense]
MVIDTSAIVAIALNENDAADIERLIADDPIRLISAATVLEATMVIETRLGDAGGREFDLWLVKIGAEVVAVDTVQADAAR
RAWRRYGKGHHAASLNHGDCFSYALAITSNEPLLFKGEDFAKTDVRRAGATPQG

Download         Length: 405 bp

>T226568 NZ_CP122517:2682129-2682236 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9747.06 Da        Isoelectric Point: 5.9111

>AT226568 WP_145630234.1 NZ_CP088014:c1136120-1135866 [Bradyrhizobium daqingense]
MALSIKDPETEQLARSLARLTGENITTATKRAIEERLRRLGGQTRKDALLEDMAEIRRRWSEMRVLDDRTPEEILGYDEH
GLPR

Download         Length: 255 bp

>AT226568 NZ_CP122517:c2682082-2682016 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References