Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataT-TacA2/DUF1778(antitoxin)
Location 4090914..4091705 Replicon chromosome
Accession NZ_CP088010
Organism Rhizobium sp. T136

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag LPB79_RS30035 Protein ID WP_225039781.1
Coordinates 4091265..4091705 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag LPB79_RS30030 Protein ID WP_024313357.1
Coordinates 4090914..4091189 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPB79_RS30005 (LPB79_30005) 4086574..4088277 - 1704 WP_007798943.1 30S ribosomal protein S1 -
LPB79_RS30010 (LPB79_30010) 4088445..4089092 - 648 WP_024313360.1 (d)CMP kinase -
LPB79_RS30015 (LPB79_30015) 4089101..4089742 - 642 WP_024313359.1 FMN-binding negative transcriptional regulator -
LPB79_RS30020 (LPB79_30020) 4089982..4090371 + 390 WP_024313358.1 TIGR02300 family protein -
LPB79_RS30030 (LPB79_30030) 4090914..4091189 + 276 WP_024313357.1 DUF1778 domain-containing protein Antitoxin
LPB79_RS30035 (LPB79_30035) 4091265..4091705 + 441 WP_225039781.1 GNAT family N-acetyltransferase Toxin
LPB79_RS30040 (LPB79_30040) 4091818..4092006 - 189 WP_141652536.1 hypothetical protein -
LPB79_RS30045 (LPB79_30045) 4092452..4092751 + 300 WP_024313354.1 hypothetical protein -
LPB79_RS30050 (LPB79_30050) 4092858..4093568 + 711 WP_024313353.1 YoaK family protein -
LPB79_RS30055 (LPB79_30055) 4093633..4094418 + 786 WP_024313352.1 YdcF family protein -
LPB79_RS30060 (LPB79_30060) 4094424..4094906 - 483 WP_024313351.1 hypothetical protein -
LPB79_RS30065 (LPB79_30065) 4095032..4095667 + 636 WP_024313350.1 trimeric intracellular cation channel family protein -
LPB79_RS30070 (LPB79_30070) 4095670..4096089 - 420 WP_024313349.1 Fur family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(21-126)

Antitoxin

Vibrio phage ICP1, Orf50

(11-84)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16046.48 Da        Isoelectric Point: 8.8797

>T226565 WP_225039781.1 NZ_CP088010:4091265-4091705 [Rhizobium sp. T136]
MDSWLKEMALHNQEQGYTRTFVIADENFKVVGYHSVCAGMIHRNDVSRSVKGSKSPTEIPIAVLARLAVDADHHGKGLGK
ALLKNALMSVVSAAQVAAFRAVIIHALDDDAVTFYKKFGFQETKNMERRLILPTKDIAASLYEATG

Download         Length: 441 bp

>T226565 NZ_CP122517:2014748-2014851 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10071.49 Da        Isoelectric Point: 4.5994

>AT226565 WP_024313357.1 NZ_CP088010:4090914-4091189 [Rhizobium sp. T136]
MSAPRKTKTVNLRIEPETHDLIARAAEVCGKSITAFMTEASVYTAQEELLDQRFIGVSADVFEAVSEQLAAPGVARDNLV
KLFQTKVDWMD

Download         Length: 276 bp

>AT226565 NZ_CP122517:c2014889-2014618 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References