Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 3834234..3834987 Replicon chromosome
Accession NZ_CP088000
Organism Stenotrophomonas rhizophila strain Bl2-2

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag LQE85_RS17605 Protein ID WP_249833189.1
Coordinates 3834234..3834671 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag LQE85_RS17610 Protein ID WP_210131158.1
Coordinates 3834718..3834987 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQE85_RS17580 (LQE85_17580) 3830569..3831189 - 621 WP_068854185.1 glutathione S-transferase -
LQE85_RS17585 (LQE85_17585) 3831430..3832740 + 1311 WP_249833188.1 NAD(P)/FAD-dependent oxidoreductase -
LQE85_RS17590 (LQE85_17590) 3832713..3833030 - 318 WP_095363054.1 hypothetical protein -
LQE85_RS17595 (LQE85_17595) 3833027..3833299 - 273 WP_095363055.1 GIY-YIG nuclease family protein -
LQE85_RS17600 (LQE85_17600) 3833620..3834237 + 618 WP_068854189.1 trimeric intracellular cation channel family protein -
LQE85_RS17605 (LQE85_17605) 3834234..3834671 - 438 WP_249833189.1 GNAT family N-acetyltransferase Toxin
LQE85_RS17610 (LQE85_17610) 3834718..3834987 - 270 WP_210131158.1 DUF1778 domain-containing protein Antitoxin
LQE85_RS17615 (LQE85_17615) 3835171..3836244 - 1074 WP_249833190.1 3-deoxy-7-phosphoheptulonate synthase -
LQE85_RS17620 (LQE85_17620) 3836547..3837710 + 1164 WP_095363057.1 serine hydrolase domain-containing protein -
LQE85_RS17625 (LQE85_17625) 3837780..3839429 - 1650 WP_093534776.1 chaperonin GroEL -
LQE85_RS17630 (LQE85_17630) 3839520..3839807 - 288 WP_068854195.1 co-chaperone GroES -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-130)

Antitoxin

Vibrio phage ICP1, Orf50

(8-82)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15594.26 Da        Isoelectric Point: 9.3960

>T226551 WP_249833189.1 NZ_CP088000:c3834671-3834234 [Stenotrophomonas rhizophila]
MDDFRCSAPPLAKWLLERARQNQASGASRCFVACDEKRRVVGYYALSAGSIAHEAAPGRIRRNMPDPIPVIVLGRLAVHA
DRAGQGIGQGLLKDAVLRSLQACGQVGARALLCHAIDEPAKAFYLKHGFIASPIHPLTLMLPLAC

Download         Length: 438 bp

>T226551 NZ_CP122512:c5445-5185 [Escherichia coli]
ATGAAGATAAGAAAAGGTGACAGACAATATTATCTGAATAAAGAAGGTGATACGTTTCATCTGGTGAAGCGAGTAAAAAC
TTTTTCTAAGTCTGCGACTTTAGGAAAAACGAAAGCAACAGTGAAAACTGTTGCCGATCTTGTTTTTCATGAGAAGGCAT
TCGACACTATCGACTTTGCCAGCGACGGATTAAGAGAGAATGATAAAGAAATTGTTTCTATGATGATTCAGGAAATGAGT
GAGGGAAAAAATGCCAAATGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9952.30 Da        Isoelectric Point: 4.7571

>AT226551 WP_210131158.1 NZ_CP088000:c3834987-3834718 [Stenotrophomonas rhizophila]
MGTASKVINFRAPADKQDLIDRAVAISGVNRTEFILEAACDRAREVLADQTQFTLNAEQLQRFNALLDAPLEDNLALRRL
LSTPAPWER

Download         Length: 270 bp

>AT226551 NZ_CP122512:c5195-4944 [Escherichia coli]
ATGCCAAATGAAAACACACCAGAAAACATTAAACGTCTGCGGCAAAAAATTGGCCTGACACAGAAAGAATGTGCCGAAAT
ATTTAGCATGAGTCCGCGTACCTGGCGTCGCAAAGAAGAACCTGTCGGAACTGCAAGCGGTACAGCACTTACACCAGTAG
AGTTTAAATTTCTTCTGCTTTTAGCTGGAGAACACCCTGATTATGTACTTTGTAAAAGGAATAAAAAGAATTCTGATTCT
GGAAGTAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References