Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1358886..1359342 Replicon chromosome
Accession NZ_CP087999
Organism Geomonas sp. RF6

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LPW11_RS05820 Protein ID WP_230997188.1
Coordinates 1358886..1359128 (+) Length 81 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LPW11_RS05825 Protein ID WP_230997189.1
Coordinates 1359118..1359342 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPW11_RS05795 (LPW11_05795) 1355231..1355737 - 507 WP_230997184.1 molybdopterin-guanine dinucleotide biosynthesis protein B -
LPW11_RS05805 (LPW11_05805) 1356415..1356816 + 402 WP_230997185.1 hypothetical protein -
LPW11_RS05810 (LPW11_05810) 1356844..1357959 + 1116 WP_230997186.1 hypothetical protein -
LPW11_RS05815 (LPW11_05815) 1358037..1358783 + 747 WP_230997187.1 ankyrin repeat domain-containing protein -
LPW11_RS05820 (LPW11_05820) 1358886..1359128 + 243 WP_230997188.1 BrnT family toxin Toxin
LPW11_RS05825 (LPW11_05825) 1359118..1359342 + 225 WP_230997189.1 BrnA antitoxin family protein Antitoxin
LPW11_RS05830 (LPW11_05830) 1359528..1359767 - 240 WP_230997190.1 hypothetical protein -
LPW11_RS05835 (LPW11_05835) 1359943..1360575 - 633 WP_230997191.1 hypothetical protein -
LPW11_RS05840 (LPW11_05840) 1361201..1362898 - 1698 WP_230997192.1 Ig-like domain-containing protein -
LPW11_RS05845 (LPW11_05845) 1363135..1363932 - 798 WP_230997193.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(3-74)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 81 a.a.        Molecular weight: 9013.20 Da        Isoelectric Point: 7.2023

>T226542 WP_230997188.1 NZ_CP087999:1358886-1359128 [Geomonas sp. RF6]
MSKSAGNKQKHGIDFDEAQSLWDDPDLLEVPVVTTDGPRFLVVGRISGKHWSGIITYRGDAIRIISVRRSRKEEIALYES

Download         Length: 243 bp

>T226542 NZ_CP122508:96417-97742 [Escherichia coli]
ATGAGCCGGAAACAGCAACGTCTGGTAATTTGGATGAACGGCATCAAAGTCGGGTACTGGGAAAAAAGCAAAGGGGTAGA
CAGCTTAGAATACCTTCCTGAATGGGTTGCTGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTGCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTGGAGCCTTTTGATCTGCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACTGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGAGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGGCCAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAGACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCGTTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAGGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAATTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCAAACTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8573.80 Da        Isoelectric Point: 7.0150

>AT226542 WP_230997189.1 NZ_CP087999:1359118-1359342 [Geomonas sp. RF6]
MKADDIDKTFDEGGDISAHLDVTKARRPEQEQKRVNVDFPLWMIQQLDKESRRLGVPRQAIIKVWVAERLEKAG

Download         Length: 225 bp

>AT226542 NZ_CP122508:96119-96412 [Escherichia coli]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGCTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGCGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCCATCCTGGGCGTAAAAATCAGCTTCTCCTCGGCAACCACCTCTTCAGAGAGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGGATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References