Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RHH(antitoxin) |
Location | 1608750..1609272 | Replicon | chromosome |
Accession | NZ_CP087993 | ||
Organism | Xylella fastidiosa subsp. multiplex strain CFBP8416 |
Toxin (Protein)
Gene name | parE | Uniprot ID | - |
Locus tag | XYFPCFBP8416_RS07220 | Protein ID | WP_004085905.1 |
Coordinates | 1608985..1609272 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A060HDF9 |
Locus tag | XYFPCFBP8416_RS07215 | Protein ID | WP_004085758.1 |
Coordinates | 1608750..1608992 (+) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XYFPCFBP8416_RS07185 (XYFPCFBP8416_007135) | 1604160..1604342 | + | 183 | WP_027700467.1 | hypothetical protein | - |
XYFPCFBP8416_RS07190 (XYFPCFBP8416_007140) | 1604626..1605552 | - | 927 | WP_004085766.1 | Grx4 family monothiol glutaredoxin | - |
XYFPCFBP8416_RS07195 (XYFPCFBP8416_007145) | 1605651..1606394 | + | 744 | WP_225621865.1 | polysaccharide deacetylase family protein | - |
XYFPCFBP8416_RS07200 (XYFPCFBP8416_007150) | 1607038..1607229 | - | 192 | WP_021358405.1 | hypothetical protein | - |
XYFPCFBP8416_RS07205 (XYFPCFBP8416_007155) | 1607647..1608066 | - | 420 | WP_004085763.1 | putative toxin-antitoxin system toxin component, PIN family | - |
XYFPCFBP8416_RS07210 (XYFPCFBP8416_007160) | 1608066..1608305 | - | 240 | WP_004085761.1 | ribbon-helix-helix domain-containing protein | - |
XYFPCFBP8416_RS07215 (XYFPCFBP8416_007165) | 1608750..1608992 | + | 243 | WP_004085758.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
XYFPCFBP8416_RS07220 (XYFPCFBP8416_007170) | 1608985..1609272 | + | 288 | WP_004085905.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
XYFPCFBP8416_RS07225 (XYFPCFBP8416_007175) | 1609360..1609926 | + | 567 | WP_004085755.1 | recombinase family protein | - |
XYFPCFBP8416_RS07230 (XYFPCFBP8416_007180) | 1609979..1611169 | - | 1191 | WP_278279195.1 | RNA-guided endonuclease TnpB family protein | - |
XYFPCFBP8416_RS07235 (XYFPCFBP8416_007185) | 1611169..1611795 | - | 627 | WP_038230952.1 | IS607 family transposase | - |
XYFPCFBP8416_RS07240 (XYFPCFBP8416_007190) | 1612025..1613299 | - | 1275 | WP_012337985.1 | pyridoxal phosphate-dependent aminotransferase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1607244..1628541 | 21297 | |
- | flank | IS/Tn | - | - | 1609360..1609926 | 566 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11159.64 Da Isoelectric Point: 5.9570
>T226526 WP_004085905.1 NZ_CP087993:1608985-1609272 [Xylella fastidiosa subsp. multiplex]
MAKSYRLTPLAEADLEEIWFYTFRHWSIEQADSYHRSLVAVFEGLAAGTKQGCPSVLPDFNKYLCGSHVVYFMDYADHLD
IIRILHQRQDTERYL
MAKSYRLTPLAEADLEEIWFYTFRHWSIEQADSYHRSLVAVFEGLAAGTKQGCPSVLPDFNKYLCGSHVVYFMDYADHLD
IIRILHQRQDTERYL
Download Length: 288 bp
>T226526 NZ_CP122507:914149-914556 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8774.77 Da Isoelectric Point: 6.9881
>AT226526 WP_004085758.1 NZ_CP087993:1608750-1608992 [Xylella fastidiosa subsp. multiplex]
MSRNTSVALGPHFTSFIDAQVQGGRYGTASDVVRAGLRLLEEHETKVKALQDALNVGHQSGEPRPFDSEVFLSRMHTQHG
MSRNTSVALGPHFTSFIDAQVQGGRYGTASDVVRAGLRLLEEHETKVKALQDALNVGHQSGEPRPFDSEVFLSRMHTQHG
Download Length: 243 bp
>AT226526 NZ_CP122507:913902-914168 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACAGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACAGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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