Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2470852..2471535 Replicon chromosome
Accession NZ_CP087992
Organism Xylella fastidiosa subsp. multiplex strain CFBP8433

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LOK81_RS11135 Protein ID WP_004086858.1
Coordinates 2470852..2471280 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LOK81_RS11140 Protein ID WP_004086856.1
Coordinates 2471281..2471535 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOK81_RS11105 (LOK81_11025) 2467406..2468167 - 762 WP_004085598.1 Bax inhibitor-1/YccA family protein -
LOK81_RS11130 (LOK81_11050) 2469368..2470762 + 1395 WP_169710402.1 hypothetical protein -
LOK81_RS11135 (LOK81_11055) 2470852..2471280 - 429 WP_004086858.1 type II toxin-antitoxin system VapC family toxin Toxin
LOK81_RS11140 (LOK81_11060) 2471281..2471535 - 255 WP_004086856.1 hypothetical protein Antitoxin
LOK81_RS11145 (LOK81_11065) 2471660..2472202 + 543 WP_154436894.1 hypothetical protein -
LOK81_RS11150 (LOK81_11070) 2472523..2472896 - 374 Protein_2170 DUF596 domain-containing protein -
LOK81_RS11155 (LOK81_11075) 2472908..2473213 - 306 WP_228762248.1 DUF769 domain-containing protein -
LOK81_RS11160 (LOK81_11080) 2473412..2473804 - 393 WP_038211775.1 DUF596 domain-containing protein -
LOK81_RS11165 (LOK81_11085) 2473815..2474072 - 258 WP_021358680.1 hemagglutinin -
LOK81_RS11170 (LOK81_11090) 2474346..2474729 - 384 WP_004086848.1 DUF596 domain-containing protein -
LOK81_RS11175 (LOK81_11095) 2474734..2475770 - 1037 Protein_2175 DUF769 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15641.79 Da        Isoelectric Point: 5.1634

>T226521 WP_004086858.1 NZ_CP087992:c2471280-2470852 [Xylella fastidiosa subsp. multiplex]
MIVLDTNVVSEAMKPEPDAAVRTWLNEQMSVTLYLSSVTLSELLFGIAVLPTSKRKDMLARTLDGLLDLFNERVLPFDTD
AARHYAELAVKARNNGRGFPTPDGYIAAIAASRGYIVASRDTSAYESSGVQVINPWQYSKQT

Download         Length: 429 bp

>T226521 NZ_CP122507:181259-181366 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9601.95 Da        Isoelectric Point: 6.4732

>AT226521 WP_004086856.1 NZ_CP087992:c2471535-2471281 [Xylella fastidiosa subsp. multiplex]
MAMLTVRNLPDEVHRALRVRAATHGRSTEAEVREILTNIVKPDERVRIGDALAILGREIGLNNEDFTTFDKVRDKTQAEP
MRFE

Download         Length: 255 bp

>AT226521 NZ_CP122507:c181211-181145 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References