Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1031429..1032183 Replicon chromosome
Accession NZ_CP087992
Organism Xylella fastidiosa subsp. multiplex strain CFBP8433

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag LOK81_RS04525 Protein ID WP_021358673.1
Coordinates 1031429..1031908 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag LOK81_RS04530 Protein ID WP_004085396.1
Coordinates 1031911..1032183 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOK81_RS04515 (LOK81_04470) 1028282..1029088 + 807 WP_154436917.1 oxidoreductase -
LOK81_RS04520 (LOK81_04475) 1029228..1031093 + 1866 WP_194957723.1 DUF5710 domain-containing protein -
LOK81_RS04525 (LOK81_04480) 1031429..1031908 - 480 WP_021358673.1 GNAT family N-acetyltransferase Toxin
LOK81_RS04530 (LOK81_04485) 1031911..1032183 - 273 WP_004085396.1 DUF1778 domain-containing protein Antitoxin
LOK81_RS04535 (LOK81_04490) 1032535..1033440 - 906 WP_004085395.1 AEC family transporter -
LOK81_RS04540 (LOK81_04495) 1033556..1034174 + 619 Protein_877 IS607 family transposase -
LOK81_RS04545 (LOK81_04500) 1034402..1036435 + 2034 WP_228762228.1 glycoside hydrolase family 3 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(33-146)

Antitoxin

Vibrio phage ICP1, Orf50

(3-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17645.42 Da        Isoelectric Point: 9.9283

>T226517 WP_021358673.1 NZ_CP087992:c1031908-1031429 [Xylella fastidiosa subsp. multiplex]
MQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVIDANQYVLGYYALAAGAVAHQEATRAIRRNMPD
PVPVMVLGRLAVDTRAQGIKLGAALLKDTVTRVQSIAENAGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIKF

Download         Length: 480 bp

>T226517 NZ_CP122503:c4671050-4670739 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10264.77 Da        Isoelectric Point: 5.0488

>AT226517 WP_004085396.1 NZ_CP087992:c1032183-1031911 [Xylella fastidiosa subsp. multiplex]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLNAPQDTNPGLNRLMA
IKAPWSISNT

Download         Length: 273 bp

>AT226517 NZ_CP122503:c4670738-4670448 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References